[HTML][HTML] Crosstalk between KRAS, SRC and YAP signaling in pancreatic cancer: interactions leading to aggressive disease and drug resistance
E Rozengurt, G Eibl - Cancers, 2021 - mdpi.com
Simple Summary Pancreatic ductal adenocarcinoma (PDAC), the most common form of
pancreatic cancer, remains one of the most lethal diseases. Current evidence, discussed in …
pancreatic cancer, remains one of the most lethal diseases. Current evidence, discussed in …
Implications of cancer stem cells in diabetes and pancreatic cancer
AG Mukherjee, UR Wanjari, AV Gopalakrishnan… - Life Sciences, 2023 - Elsevier
This review provides a detailed study of pancreatic cancer (PC) and the implication of
different types of cancers concerning diabetes. The combination of anti-diabetic drugs with …
different types of cancers concerning diabetes. The combination of anti-diabetic drugs with …
[HTML][HTML] Oncogenomic changes in pancreatic cancer and their detection in stool
H Sammallahti, VK Sarhadi, A Kokkola, R Ghanbari… - Biomolecules, 2022 - mdpi.com
Pancreatic cancer (PC) is an aggressive malignancy with a dismal prognosis. To improve
patient survival, the development of screening methods for early diagnosis is pivotal …
patient survival, the development of screening methods for early diagnosis is pivotal …
[HTML][HTML] Serum miRNA profiling for early PDAC diagnosis and prognosis: a retrospective study
A Aita, C Millino, C Sperti, B Pacchioni, M Plebani… - Biomedicines, 2021 - mdpi.com
Background: Tumor stage predicts pancreatic cancer (PDAC) prognosis, but prolonged and
short survivals have been described in patients with early-stage tumors. Circulating …
short survivals have been described in patients with early-stage tumors. Circulating …
[PDF][PDF] The heterogeneity of CAFs and immune cell populations in the tumor microenvironment of pancreatic adenocarcinoma
M Diab, BF El-Rayes - J Cancer Metastasis Treat, 2022 - academia.edu
Over the past decade, researchers have identified and characterized the diverse cell
populations within the tumor microenvironment of pancreatic cancer. The interplay between …
populations within the tumor microenvironment of pancreatic cancer. The interplay between …
[HTML][HTML] Glycogen synthase kinase 3β: the nexus of chemoresistance, invasive capacity, and cancer stemness in pancreatic cancer
M Uehara, T Domoto, S Takenaka… - Cancer Drug …, 2024 - ncbi.nlm.nih.gov
The treatment of pancreatic cancer remains a significant clinical challenge due to the limited
number of patients eligible for curative (R0) surgery, failures in the clinical development of …
number of patients eligible for curative (R0) surgery, failures in the clinical development of …
Metastasis suppressor genes in pancreatic cancer: an update
A Bhattacharya, A Santhoshkumar, H Kurahara… - Pancreas, 2021 - journals.lww.com
Pancreatic cancer, especially pancreatic ductal adenocarcinoma (PDAC), has for long
remained a deadly form of cancer characterized by high mortality rates resulting from …
remained a deadly form of cancer characterized by high mortality rates resulting from …
Design of SF3B1 subunit modulators of the SF3B spliceosome complex
O Randazzo - 2022 - research.vu.nl
The subject of this dissertation is the search for new therapeutic strategies for pancreatic
cancer and aims to implement a Drug Discovery process for the rational design and …
cancer and aims to implement a Drug Discovery process for the rational design and …
[PDF][PDF] Serum miRNA Profiling for Early PDAC Diagnosis and Prognosis: A Retrospective Study. Biomedicines 2021, 9, 845
A Aita, C Millino, C Sperti, B Pacchioni… - MicroRNA in Solid …, 2021 - mdpi.com
Background: Tumor stage predicts pancreatic cancer (PDAC) prognosis, but prolonged and
short survivals have been described in patients with early-stage tumors. Circulating …
short survivals have been described in patients with early-stage tumors. Circulating …