Inflammation resolution in environmental pulmonary health and morbidity

JM Marzec, SS Nadadur - Toxicology and applied pharmacology, 2022 - Elsevier
Inflammation and resolution are dynamic processes comprised of inflammatory activation
and neutrophil influx, followed by mediator catabolism and efferocytosis. These critical …

Association of immune cell recruitment and BPD development

M Heydarian, C Schulz, T Stoeger… - Molecular and Cellular …, 2022 - Springer
In the neonatal lung, exposure to both prenatal and early postnatal risk factors converge into
the development of injury and ultimately chronic disease, also known as bronchopulmonary …

[HTML][HTML] Targeted sphingolipid analysis in chickens suggests different mechanisms of fumonisin toxicity in kidney, lung, and brain

P Guerre, M Matard-Mann, PN Collén - Food and Chemical Toxicology, 2022 - Elsevier
Most of the toxic effects of fumonisins can be related to sphingolipid alteration, but there is
little sphingolipidomic data in animals fed fumonisins in organs other than the liver. This …

Maternal vitamin D–related metabolome and offspring risk of asthma outcomes

M Kim, N Brustad, M Ali, G Gürdeniz, M Arendt… - Journal of Allergy and …, 2023 - Elsevier
Background Gestational vitamin D deficiency is implicated in development of respiratory
diseases in offspring, but the mechanism underlying this relationship is unknown. Objective …

Sphingosine kinase 1-specific inhibitor PF543 reduces goblet cell metaplasia of bronchial epithelium in an acute asthma model

T Sudhadevi, SJ Ackerman, A Jafri… - … of Physiology-Lung …, 2024 - journals.physiology.org
Sphingosine kinase 1 (SPHK1) has been shown to play a key role in the pathogenesis of
asthma where SPHK1-generated sphingosine-1-phosphate (S1P) is known to mediate …

[HTML][HTML] Association between bronchopulmonary dysplasia and death or neurodevelopmental impairment at 3 years in preterm infants without severe brain injury

W Li, Y Wang, J Song, C Zhang, Y Xu, F Xu… - Frontiers in …, 2023 - frontiersin.org
Objective We investigated the association between bronchopulmonary dysplasia (BPD) and
3 years death or neurodevelopmental impairment (NDI) in very preterm infants without …

Pollen‐Inspired Shell–Core Aerosol Particles Capable of Brownian Motion for Pulmonary Vascularization

Y Chen, W Chen, X Xiang, L Deng, J Qian… - Advanced …, 2023 - Wiley Online Library
Nebulization is the most widely used respiratory delivery technique with non‐invasive
properties. However, nebulized drugs often fail to function due to the excretion and immune …

Investigation of the miRNA-mRNA Regulatory Circuits and Immune Signatures Associated with Bronchopulmonary Dysplasia

S Li, S Liang, S Xie, H Chen, H Huang… - Journal of …, 2024 - Taylor & Francis
Background Bronchopulmonary dysplasia (BPD) has become a major cause of morbidity
and mortality in preterm infants worldwide, yet its pathogenesis and underlying mechanisms …

Protective Actions of α-Tocopherol on Cell Membrane Lipids of Paraquat-Stressed Human Astrocytes Using Microarray Technology, MALDI-MS and Lipidomic …

L Sánchez-Sánchez, R Fernández, MD Ganfornina… - Antioxidants, 2022 - mdpi.com
Cellular senescence is one of the main contributors to some neurodegenerative disorders.
The early detection of senescent cells or their related effects is a key aspect in treating …

Ceramides as therapeutic targets in bronchopulmonary dysplasia

A Hamraghani - 2024 - ruor.uottawa.ca
Bronchopulmonary dysplasia (BPD) is a chronic lung disorder associated with extremely
premature birth, resulting from arrested development of the microvasculature and …