A 60-year-old woman with nonalcoholic steatohepatitis (NASH) cirrhosis complicated
ascites who is taking diuretics presents to clinic for follow-up with lower extremity edema …

Abstract Background and Aims: Refractory ascites represents a significant complication of
decompensated cirrhosis, associated with increased mortality rates. The aim of this meta …

Background This large-scale post-marketing surveillance study (START study) evaluated the
effectiveness and safety of tolvaptan in Japanese liver cirrhosis patients with hepatic edema …

Hypervolemic (dilutional) hyponatremia is the most common dysnatremia in cirrhosis, with a
prevalence close to 50% in patients with ascites, while hypovolemic hyponatremia occurs in …

Aim Despite accumulating evidence concerning the efficacy of tolvaptan in the treatment of
body fluid retention or hyponatremia, the effect of tolvaptan on the prognosis of patients with …

Background This study investigated time-course changes in skeletal muscle volume per
year with tolvaptan in patients with refractory ascites that was unresponsive to loop diuretics …

Abstract Background and Aim The prognosis of cirrhotic patients with hepatic edema is poor.
Although several short‐term predictors of tolvaptan (novel diuretic agent) treatment for such …

Aim Cell‐free and concentrated ascites reinfusion therapy (CART) and large‐volume
paracentesis (LVP) with albumin infusion are useful for managing refractory ascites (RA) …

Aim Prognosis of liver cirrhosis patients is poor when ascites is present and liver function is
impaired, but such up‐to‐date information from a large‐scale, real‐world setting is limited in …

Background Acute kidney injury (AKI) is associated with liver cirrhosis (LC), water retention,
diuretics to treat water retention, and a poor prognosis. Urinary neutrophil gelatinase …