Metabolism of the endocannabinoid anandamide: open questions after 25 years

M Maccarrone - Frontiers in molecular neuroscience, 2017 - frontiersin.org
Cannabis extracts have been used for centuries, but its main active principle∆ 9-
tetrahydrocannabinol (THC) was identified about 50 years ago. Yet, it is only 25 years ago …

Targeting endocannabinoid signaling: FAAH and MAG lipase inhibitors

N van Egmond, VM Straub… - Annual Review of …, 2021 - annualreviews.org
Inspired by the medicinal properties of the plant Cannabis sativa and its principal
component (−)-trans-Δ9-tetrahydrocannabinol (THC), researchers have developed a variety …

The role of endocannabinoid pathway in the neuropathology of Alzheimer's disease: Can the inhibitors of MAGL and FAAH prove to be potential therapeutic targets …

S Bajaj, S Jain, P Vyas, S Bawa, D Vohora - Brain Research Bulletin, 2021 - Elsevier
Alzheimer's disease is a neurodegenerative disease characterized by progressive decline of
cognitive function in combination with neuronal death. Current approved treatment target …

Investigating the modulation of the endocannabinoid system by probiotic Lactiplantibacillus plantarum IMC513 in a zebrafish model of di-n-hexyl phthalate exposure

R Prete, C Merola, N Garcia-Gonzalez, F Fanti… - Scientific Reports, 2024 - nature.com
Environmental pollutants used as plasticizers in food packaging and in thousands of
everyday products have become harmful for their impact on human health. Among them …

Potential Therapeutic Targets to Modulate the Endocannabinoid System in Alzheimer's Disease

H Kanwal, M Sangineto, M Ciarnelli… - International Journal of …, 2024 - mdpi.com
Alzheimer's disease (AD), the most common neurodegenerative disease (NDD), is
characterized by chronic neuronal cell death through progressive loss of cognitive function …

Long‐term effect of oral cannabidiol administration to healthy adult dogs on tear production, intraocular pressure, and tear concentrations

HE Jost, K Spitznagel, IC Alvarenga… - Veterinary …, 2024 - Wiley Online Library
Objective To determine the chronic effects of oral cannabidiol (CBD) use on tear production,
intraocular pressure (IOP), and concentration of CBD in tears of healthy dogs. Animals …

El sistema endocannabinoide en la enfermedad de alzheimer: implicación de la enzima amidohidrolasa de ácidos grasos

G Ruiz Pérez - 2021 - euskadi.osasuna.ezagutzarenataria …
La planta Cannabis sativa ha sido utilizada desde la antigüedad por la humanidad con fines
terapéuticos y recreativos. El interés por esclarecer los efectos derivados de su uso llevó al …

[引用][C] Avaliação antitumoral de amidas graxas derivadas de triglicerídeos de óleo de andiroba (Carapa guianensis aublet) em linhagem celular de glioma in vitro

NM SILVA - 2022 - Universidade Federal do Pará