Background The etiology of community-acquired pneumonia (CAP) has evolved since the
beginning of the antibiotic era. Recent guidelines encourage immediate empiric antibiotic …

Streptococcus pneumoniae (the pneumococcus) is an important human pathogen. Its
virulence is largely due to its polysaccharide capsule, which shields it from the host immune …

6.1. Background The incidence of tuberculosis (TB) is a concern at the start of the third
millennium, particularly with the increase of multiresistant (MDR-TB) and extended resistant …

Aim To present a systematic literature review (SLR) on efficacy, immunogenicity and safety
of vaccination in adult patients with autoimmune inflammatory rheumatic diseases (AIIRD) …

Untangling the interdependency of infections, immunity and frailty may help to clarify their
roles in the maintenance of health in aging individuals, and the recent COVID-19 pandemic …

Pneumococcal polysaccharide vaccines (PPVs) and conjugate vaccines (PCVs), of which
PPV23 and PCV13 are the current front runners, have had a significant, beneficial impact on …

Background: Pneumococcal disease remains a public health priority in adults. Safety and
immunogenicity of 2 different formulations of 15-valent pneumococcal conjugate vaccine …

This study describes the effects of the introduction of universal infant pneumococcal
conjugate vaccination in 2006 on invasive pneumococcal disease (IPD) among children and …

The emergence of extremely resistant and panresistant Gram-negative bacilli, such as
Acinetobacter baumannii, requires consideration of nonantimicrobial therapeutic …

Pneumonia is one of the main causes of morbidity and mortality in the elderly. The elderly
population has exponentially increased in the last decades and the current epidemiological …