Structural hippocampal abnormalities are common in many neurological and psychiatric
disorders, and variation in hippocampal measures is related to cognitive performance and …

Schizophrenia is a neurodevelopmental disorder with genetic predisposition, and stress has
long been linked to its etiology. While stress affects all stages of the illness, increasing …

Abstract Background and Hypothesis Individuals at clinical high risk for psychosis (CHR-p)
are less fit than nonclinical peers and show hippocampal abnormalities that relate to clinical …

Despite strong evidence of the neurodevelopmental origins of psychosis, current
pharmacological treatment is not usually initiated until after a clinical diagnosis is made, and …

Evidence points toward a relationship between longer duration of untreated psychosis
(DUP) and worse long-term outcomes in patients with first episode psychosis (FEP), but the …

Hippocampus-related cognitive deficits in working and verbal memory are frequent in
schizophrenia, and hippocampal volume loss, particularly in the cornu ammonis (CA) …

Cross-sectional studies suggest that hippocampal volume declines across stages of
psychosis. In contrast, longitudinal studies indicate that hippocampal volume is stable in the …

Low hippocampal volume is a consistent finding in schizophrenia and across the psychosis
spectrum. However, there is a lack of studies investigating longitudinal hippocampal …

Background: Emerging evidence supports the antipsychotic effect of cannabidiol, a non-
intoxicating component of cannabis, in people with psychosis. Preclinical findings suggest …

Numerous studies have implicated involvement of the hippocampus in the etiology and
expression of schizophrenia-spectrum psychopathology, and reduced hippocampal volume …