AgRP/NPY and POMC neurons in the arcuate nucleus and their potential role in treatment of obesity

MS Vohra, K Benchoula, CJ Serpell, WE Hwa - European journal of …, 2022 - Elsevier
Obesity is a major health crisis affecting over a third of the global population. This
multifactorial disease is regulated via interoceptive neural circuits in the brain, whose …

Hypothalamic regulatory mechanisms of aging

PM Masliukov, AD Nozdrachev - Journal of Evolutionary Biochemistry and …, 2021 - Springer
The hypothalamus is the most important integrator of functions of the autonomous,
endocrine, somatic nervous systems; it is involved in the regulation of rhythmic processes …

Hippocampal BDNF overexpression or microR124a silencing reduces anxiety-and autism-like behaviors in rats

A Bahi - Behavioural Brain Research, 2017 - Elsevier
Abstract MicroRNA124a (miR124a) has emerged recently as a key player for multiple
neuropsychiatric disorders including depression, anxiety, alcoholism, and cocaine addiction …

Regulatory role of microRNAs in brain development and function

C Yapijakis - GeNeDis 2018: Genetics and Neurodegeneration, 2020 - Springer
MicroRNAs (miRNAs) are small non-coding RNA molecules of about 20–22 nucleotides.
After their posttranscriptional maturation, miRNAs are loaded into the ribonucleoprotein …

Fractional amplitude of low-frequency fluctuations associated with μ-opioid and dopamine receptor distributions in the central nervous system after high-intensity …

H Boecker, M Daamen, A Maurer… - Frontiers in …, 2024 - frontiersin.org
Introduction Dopaminergic, opiod and endocannabinoid neurotransmission are thought to
play an important role in the neurobiology of acute exercise and, in particular, in mediating …

Mechanisms driving palmitate-mediated neuronal dysregulation in the hypothalamus

CV Lieu, N Loganathan, DD Belsham - Cells, 2021 - mdpi.com
The hypothalamus maintains whole-body homeostasis by integrating information from
circulating hormones, nutrients and signaling molecules. Distinct neuronal subpopulations …

MicroRNAs in psychological stress reactions and their use as stress-associated biomarkers, especially in human saliva

C Wiegand, A Savelsbergh, P Heusser - Biomedicine Hub, 2018 - karger.com
MicroRNAs (miRNAs) play a central role in the regulation of many cellular processes
including physiological and psychological stress reaction pathways. Psychological stress is …

miR-124 antagonizes the antidepressant-like effects of standardized gypenosides in mice

LT Yi, RH Mu, SQ Dong, SS Wang… - Journal of …, 2018 - journals.sagepub.com
Our previous study demonstrated that gypenosides produced antidepressant-like effects in
mice exposed to chronic mild stress in a brain-derived neurotrophic factor-dependent …

Environmental exposures, the epigenome, and African American women's health

JE Ohm - Journal of Urban Health, 2019 - Springer
Stress is a common feature of modern life, but both the extent of exposure to stressors and
the downstream effects of these stress exposures can vary considerably among individuals …

Let-7a, mir-9, mir-132, and mir-218 microRNA Expression in the Dorsomedial and Ventromedial Hypothalamic Nuclei during Aging in Rats

VV Porseva, NY Levshin, KY Moiseev… - Advances in …, 2021 - Springer
The hypothalamus is involved in the regulation of biological rhythms, integration of
autonomic, endocrine, and behavioral functions and may also contribute in aging …