Immune checkpoint of B7-H3 in cancer: from immunology to clinical immunotherapy

B Zhao, H Li, Y Xia, Y Wang, Y Wang, Y Shi… - Journal of Hematology & …, 2022 - Springer
Immunotherapy for cancer is a rapidly developing treatment that modifies the immune
system and enhances the antitumor immune response. B7-H3 (CD276), a member of the B7 …

Melanoma management: from epidemiology to treatment and latest advances

J Lopes, CMP Rodrigues, MM Gaspar, CP Reis - Cancers, 2022 - mdpi.com
Simple Summary Melanoma is a major public health issue that claims the lives of thousands
of people every year. Furthermore, the outlook for the coming years is not encouraging with …

Trial watch: Dendritic cell (DC)-based immunotherapy for cancer

RS Laureano, J Sprooten, I Vanmeerbeerk… - …, 2022 - Taylor & Francis
Dendritic cell (DC)-based vaccination for cancer treatment has seen considerable
development over recent decades. However, this field is currently in a state of flux toward …

Nano-drug delivery system targeting tumor microenvironment: a prospective strategy for melanoma treatment

M Xu, S Li - Cancer Letters, 2023 - Elsevier
Melanoma, the most aggressive form of cutaneous malignancy arising from melanocytes, is
frequently characterized by metastasis. Despite considerable progress in melanoma …

Current molecular and clinical insights into uveal melanoma

M Fallico, G Raciti, A Longo… - International …, 2021 - spandidos-publications.com
Uveal melanoma (UM) represents the most prominent primary eye cancer in adults. With an
incidence of approximately 5 cases per million individuals annually in the United States, UM …

Molecular characteristics and therapeutic implications of Toll-like receptor signaling pathway in melanoma

H Guan, X Chen, J Liu, J Sun, H Guo, Y Jiang… - Scientific Reports, 2023 - nature.com
Melanoma is a malignant tumor of melanocytes and is often considered immunogenic
cancer. Toll-like receptor-related genes are expressed differently in most types of cancer …

Recent advances and trends in the applications of MXene nanomaterials for tissue engineering and regeneration

Y Zhong, S Huang, Z Feng, Y Fu… - Journal of Biomedical …, 2022 - Wiley Online Library
MXene, as a new two‐dimensional nanomaterial, is endowed with lots of particular
properties, such as large surface area, excellent conductivity, biocompatibility …

Advances in Nonviral mRNA Delivery Materials and Their Application as Vaccines for Melanoma Therapy

B Neill, AR Romero, OS Fenton - ACS Applied Bio Materials, 2023 - ACS Publications
Messenger RNA (mRNA) vaccines are promising platforms for cancer immunotherapy
because of their potential to encode for a variety of tumor antigens, high tolerability, and …

IFN-γ and TNF induce senescence and a distinct senescence-associated secretory phenotype in melanoma

L Homann, M Rentschler, E Brenner, K Böhm… - Cells, 2022 - mdpi.com
Immune checkpoint blockade (ICB) therapy is a central pillar of melanoma treatment leading
to durable response rates. Important mechanisms of action of ICB therapy include …

The colony stimulating factor-1 receptor (CSF-1R)-mediated regulation of microglia/macrophages as a target for neurological disorders (Glioma, stroke)

C Barca, C Foray, S Hermann, U Herrlinger… - Frontiers in …, 2021 - frontiersin.org
Immunomodulatory therapies have fueled interest in targeting microglial cells as part of the
innate immune response after infection or injury. In this context, the colony-stimulating factor …