ABSTRACT NXL104 is a potent inhibitor of class A and C serine β-lactamases, including
KPC carbapenemases. Native and NXL104-inhibited TEM-1 and P99 β-lactamases …

A series of phosphorylated flavonoids were synthesized and investigated in vitro as
inhibitors of pancreatic cholesterol esterase (CEase) and acetylcholinesterase (AChE). The …

Abstract A library of forty 7, 8-benzoflavone derivatives was synthesized and evaluated for
their inhibitory potential against cholesterol esterase (CEase). Among all the synthesized …

Abstract A series of 2-(substituted) phenyl and 2-indolyl quinoline derivatives (10a–l) was
synthesized by an efficient microwave-assisted, trifluoroacetic acid-catalyzed, solvent-free …

Pancreatic cholesterol esterase (CEase) is a serine hydrolase involved in the hydrolysis of
variety of lipids and transport of free cholesterol. In this study, pharmacophore hypotheses …

Five flavones possessing one to four phenolic groups were fully phosphorylated efficiently
and the obtained compounds showed excellent pancreatic cholesterol esterase (CEase) …

The reaction of various alkyl cinnamyl ethers with CSI afforded the corresponding
cinnamylamines with various protecting groups, such as-NHMoc,-NHiPoc,-NHCbz,-NHPnz …

Human pancreatic cholesterol esterase (hCEase) is one of the lipases found to involve in
the digestion of large and broad spectrum of substrates including triglycerides …

Alkane-1-N-butylcarbamate-n-ols (1–7) and 1, n-alkane-di-N-butylcarbamates (8–14) are
potent pseudo-substrate inhibitors of acetylcholinesterase. For inhibitors 1–7, the pre-steady …

Nitrophenyl-N-substituted carbamates (1) are characterized as pseudosubstrate inhibitors of
acetylcholinesterase. The first step is formation of the enzyme-inhibitor tetrahedral …