[HTML][HTML] A novel function for platelet-derived growth factor D: induction of osteoclastic differentiation for intraosseous tumor growth

W Huang, Y Fridman, RD Bonfil, CV Ustach… - Oncogene, 2012 - nature.com
Although increasing evidence suggests a critical role for platelet-derived growth factor
(PDGF) receptor β (β-PDGFR) signaling in prostate cancer (PCa) progression, the precise …

Osteogenic differentiation induced by bone morphogenetic proteins can be suppressed by platelet‐released supernatant in vitro

R Gruber, B Kandler, MB Fischer… - Clinical oral implants …, 2006 - Wiley Online Library
Both bone morphogenetic proteins (BMPs) and growth factors released from activated
platelets both occur at sites of bone regeneration but their functional relationship to regulate …

The effect of the dual PI3K and mTOR inhibitor BEZ235 on tumour growth and osteolytic bone disease in multiple myeloma

ZY Gan, S Fitter, K Vandyke, LB To… - European journal of …, 2015 - Wiley Online Library
The plasma cell malignancy multiple myeloma (MM) is unique among haematological
malignancies in its capacity to cause osteoclast‐mediated skeletal destruction. The …

[HTML][HTML] Glycosaminoglycans mimetics potentiate the clonogenicity, proliferation, migration and differentiation properties of rat mesenchymal stem cells

G Frescaline, T Bouderlique, MB Huynh… - Stem cell …, 2012 - Elsevier
Successful use of stem cell-based therapeutic products is conditioned by transplantation of
optimized cells in permissive microenvironment. Mesenchymal stem cell (MSC) fates are …

中药骨康含药血清对骨质疏松性骨折愈合过程中血小板衍生生长因子表达的影响

魏合伟, 林一峰, 曲崇正, 赵可伟 - 中国组织工程研究与临床康复, 2008 - cqvip.com
背景: 成骨细胞的同种异体移植, 促进骨折愈合的研究正引起重视. 中药在促进骨折愈合方面已有
确切疗效. 将二者结合起来所发挥的综合优势还需要进一步证实. 目的: 探讨中药骨康含药血清 …

Physical activity improves age‐related decline in the osteogenic potential of rats' bone marrow‐derived mesenchymal stem cells

RCR Hell, NM Ocarino, JN Boeloni, JF Silva… - Acta …, 2012 - Wiley Online Library
Aim: To examine whether physical activity increases osteogenic differentiation of bone
marrow mesenchymal stem cells (BMMSC s) from adult rats compared with young rats …

Combined effect of three types of biophysical stimuli for bone regeneration

KS Kang, JM Hong, YH Jeong, YJ Seol… - … Engineering Part A, 2014 - liebertpub.com
Pretreatment using various types of biophysical stimuli could provide appropriate potential to
cells during construction of the engineered tissue in vitro. We hypothesized that multiple …

BMP‐2 and bFGF release and in vitro effect on human osteoblasts after adsorption to bone grafts and biomaterials

FG Draenert, AL Nonnenmacher… - Clinical Oral …, 2013 - Wiley Online Library
Objectives Combination of scaffolds and growth factors is a promising option for several
clinical problems in bone biomaterials. Simplified growth factor loading by adsorption from …

Doxycycline counteracts bone morphogenic protein 2–induced osteogenic mediators

M Muthukuru, J Sun - Journal of periodontology, 2013 - Wiley Online Library
Background: Microbial colonization during wound healing may exaggerate the inflammatory
response and could adversely affect the outcome of periodontal regeneration. Bone …

[HTML][HTML] Cooperative effects in differentiation and proliferation between PDGF-BB and matrix derived synthetic peptides in human osteoblasts

T Vordemvenne, JRJ Paletta, R Hartensuer… - BMC musculoskeletal …, 2011 - Springer
Background Enhancing osteogenic capabilities of bone matrix for the treatment of fractures
and segmental defects using growth factors is an active area of research. Recently, synthetic …