Regulation of microtubule dynamics, mechanics and function through the growing tip
NB Gudimchuk, JR McIntosh - Nature reviews Molecular cell biology, 2021 - nature.com
Microtubule dynamics and their control are essential for the normal function and division of
all eukaryotic cells. This plethora of functions is, in large part, supported by dynamic …
all eukaryotic cells. This plethora of functions is, in large part, supported by dynamic …
Stimuli-responsive polymer-based nanosystems for cancer theranostics
D Wei, Y Sun, H Zhu, Q Fu - ACS nano, 2023 - ACS Publications
Stimuli-responsive polymers can respond to internal stimuli, such as reactive oxygen
species (ROS), glutathione (GSH), and pH, biological stimuli, such as enzymes, and external …
species (ROS), glutathione (GSH), and pH, biological stimuli, such as enzymes, and external …
A comprehensive insight into fungal enzymes: Structure, classification, and their role in mankind's challenges
H El-Gendi, AK Saleh, R Badierah, EM Redwan… - Journal of Fungi, 2021 - mdpi.com
Enzymes have played a crucial role in mankind's challenges to use different types of
biological systems for a diversity of applications. They are proteins that break down and …
biological systems for a diversity of applications. They are proteins that break down and …
Strategies and lessons learned from total synthesis of taxol
L Min, JC Han, W Zhang, CC Gu, YP Zou… - Chemical …, 2023 - ACS Publications
Taxol (paclitaxel), the most well-known taxane diterpenoid, is the best-selling natural-source
anticancer drug ever produced and one of the most common prescriptions in the treatment of …
anticancer drug ever produced and one of the most common prescriptions in the treatment of …
A comprehensive review on graphene oxide-based nanocarriers: Synthesis, functionalization and biomedical applications
AD Sontakke, S Tiwari, MK Purkait - FlatChem, 2023 - Elsevier
The biomedical and nanomedicine sectors have bloomed in the last two decades with the
technological advancements in nanoscience. The significance of nanotechnology for …
technological advancements in nanoscience. The significance of nanotechnology for …
Advancements in dextran-based nanocarriers for treatment and imaging of breast cancer
Breast cancer is the most prevalent type of cancer worldwide, particularly among women,
with substantial side effects after therapy. Despite the availability of numerous therapeutic …
with substantial side effects after therapy. Despite the availability of numerous therapeutic …
Molecular glue discovery: current and future approaches
JA Dewey, C Delalande, SA Azizi, V Lu… - Journal of medicinal …, 2023 - ACS Publications
The intracellular interactions of biomolecules can be maneuvered to redirect signaling,
reprogram the cell cycle, or decrease infectivity using only a few dozen atoms. Such …
reprogram the cell cycle, or decrease infectivity using only a few dozen atoms. Such …
Reconstitution of early paclitaxel biosynthetic network
JCT Liu, R De La Peña, C Tocol, ES Sattely - Nature Communications, 2024 - nature.com
Paclitaxel is an anticancer therapeutic produced by the yew tree. Over the last two decades,
a significant bottleneck in the reconstitution of early paclitaxel biosynthesis has been the …
a significant bottleneck in the reconstitution of early paclitaxel biosynthesis has been the …
Thymus vulgaris oil nanoemulsion: synthesis, characterization, antimicrobial and anticancer activities
Essential oil nanoemulsions have received much attention due to their biological activities.
Thus, a thyme essential oil nanoemulsion (Th-nanoemulsion) was prepared using a safe …
Thus, a thyme essential oil nanoemulsion (Th-nanoemulsion) was prepared using a safe …
Paclitaxel resistance related to nuclear envelope structural sturdiness
Abstract Taxanes (Taxol/paclitaxel, Docetaxel/taxotere) are a key group of successful drugs
commonly used in chemotherapy to treat several major malignant tumors also as a front-line …
commonly used in chemotherapy to treat several major malignant tumors also as a front-line …