Cytokines are involved in intestinal homeostasis and pathological processes associated
with inflammatory bowel disease (IBD). The biological effects of cytokines, including several …

Inflammatory bowel disease is characterized by defects in epithelial function and
dysregulated inflammatory signaling by lamina propria mononuclear cells including …

In 2018, the pan-Janus kinase (JAK) inhibitor tofacitinib was launched for the treatment of
ulcerative colitis (UC). Although tofacitinib has proven efficacious in patients with active UC …

Although tolerogenic dendritic cell-derived exosomes (TolDex) have emerged as promising
therapeutics for rheumatoid arthritis (RA), their clinical applications have been hampered by …

Insights into the pathogenesis of inflammatory bowel diseases (IBDs) have provided
important information for the development of therapeutics. Levels of interleukin 23 (IL23) and …

Several studies are described that contribute to the systematic exploration of new aspects of
digestion, fermentation, and biological activities of pectic polysaccharides (PPS) leading to a …

Inflammatory bowel diseases, such as ulcerative colitis and Crohn's disease, are disabling
conditions characterised by chronic, relapsing inflammation of the gastrointestinal tract …

Non-infectious uveitis (NIU) refers to various intraocular inflammatory disorders responsible
for severe visual loss. Cytokines participate in the regulation of ocular homeostasis and NIU …

Inflammatory bowel disease (IBD) is a chronic inflammatory disorder of the gastrointestinal
tract that consists of Crohn's disease (CD) and ulcerative colitis (UC). Cytokines are thought …

Macrophages are critical mediators of intestinal defense and homeostasis. However,
uncontrolled proinflammatory macrophage activity may contribute to chronic conditions such …