Imidazole and 1, 2, 4-triazole-based derivatives gifted with antitubercular activity: cytotoxicity and computational assessment

D Zampieri, F Cateni, M Moneghini… - Current topics in …, 2019 - ingentaconnect.com
Background: Mycobacterium Tuberculosis (Mtb) is the causative pathogen of Tuberculosis
(TB) and outbreaks are more common among immunosuppressed persons infected with …

Structure activity relationship studies of gymnemic acid analogues for antidiabetic activity targeting PPARγ

P Tiwari, P Sharma, F Khan… - … -Aided Drug Design, 2015 - ingentaconnect.com
Diabetes accounts for high mortality rate worldwide affecting million of lives annually. Global
prevalence of diabetes and its rising frequency makes it a key area of research in drug …

Identification of dual natural inhibitors for chronic myeloid leukemia by virtual screening, molecular dynamics simulation and ADMET analysis

H Kumar, U Raj, S Srivastava, S Gupta… - Interdisciplinary …, 2016 - Springer
Chronic myeloid leukemia (CML) is a disease of bone marrow stem cells caused by
excessive growth and accumulation of granulocytes in the blood. Aberrant expression of the …

[PDF][PDF] Potensi Biji Duwet (Syzygium cumini (L.)(Skeels.)) Sebagai Imunomodulator Pendamping Kemoterapi: Sebuah Ulasan

AS Tafrihani, CMP Gono, N Natasia, M Ikawati - J Pharm Sci, 2021 - scholar.archive.org
Mekanisme pertahanan sel kanker terhadap sistem imun tubuh merupakan ancaman bagi
keberhasilan terapi kanker. Agen kemoterapi efektif dalam membantu proses eliminasi sel …

High throughput virtual screening and in silico ADMET analysis for rapid and efficient identification of potential PAP248-286 aggregation inhibitors as anti-HIV agents

R Malik, D Bunkar, BS Choudhary, S Srivastava… - Journal of Molecular …, 2016 - Elsevier
Human semen is principal vehicle for transmission of HIV-1 and other enveloped viruses.
Several endogenous peptides present in semen, including a 39-amino acid fragments of …

[HTML][HTML] Anticancer activities of saponins and quinones group through oxidative stress and glycolysis inhibition via in Silico studies

HN Mustofa, HL Wiraswati… - Biomedical and …, 2020 - biomedpharmajournal.org
One of the known causes of cancer is imbalance production between reactive oxygen
species (ROS) and antioxidant defense within the cell. Under oxidative stress conditions …

IM-133N modulates cytokine secretion by RAW264. 7 and THP-1 cells

RS Varma, KP Guruprasad… - Journal of …, 2016 - Taylor & Francis
An indigenous herbal extract IM-133N containing extracts of Prosopis glandulosa Torr and
Symplocos racemosa Roxb were evaluated for potential immunomodulatory effects using …

Synthesis, cytotoxicity, apoptosis and molecular docking studies of novel phenylbutyrate derivatives as potential anticancer agents

A Mostoufi, R Baghgoli, M Fereidoonnezhad - Computational Biology and …, 2019 - Elsevier
Phenylbutyrate (PB), a small aromatic fatty acid, has been known as an interesting
compound with the ability of anti-proliferation and cell growth inhibition in cancer cells. In the …

Cu/Ag mediated peroxide-free synthesis of benzoylated naphthol derivatives

SP Kumari, P Suresh, V Muthukumar, SS Ganesan - Tetrahedron Letters, 2020 - Elsevier
A peroxide-free methodology was developed for the synthesis of benzoylated
naphthol/phenol derivatives through oxidative deamination reaction performed under …

In-silico approaches to study therapeutic efficacy of nutraceuticals

R Kumar, AK Singh, A Gupta, AK Pandey - … : An in-silico and in-vitro …, 2019 - Springer
Medicinal plants are sources of bioactive compounds for curing ailments since ages. In
absence of modern analytical techniques during earlier period, characterization of plant …