Exercise and metabolic health: beyond skeletal muscle

JP Thyfault, A Bergouignan - Diabetologia, 2020 - Springer
Regular exercise is a formidable regulator of insulin sensitivity and overall systemic
metabolism through both acute events driven by each exercise bout and through chronic …

Diabetes mellitus and its metabolic complications: the role of adipose tissues

L Dilworth, A Facey, F Omoruyi - International journal of molecular …, 2021 - mdpi.com
Many approaches have been used in the effective management of type 2 diabetes mellitus.
A recent paradigm shift has focused on the role of adipose tissues in the development and …

Effects of exercise to improve cardiovascular health

K Pinckard, KK Baskin, KI Stanford - Frontiers in cardiovascular …, 2019 - frontiersin.org
Obesity is a complex disease that affects whole body metabolism and is associated with an
increased risk of cardiovascular disease (CVD) and Type 2 diabetes (T2D). Physical …

Exercise adaptations: molecular mechanisms and potential targets for therapeutic benefit

SL McGee, M Hargreaves - Nature Reviews Endocrinology, 2020 - nature.com
Exercise is fundamental for good health, whereas physical inactivity underpins many chronic
diseases of modern society. It is well appreciated that regular exercise improves metabolism …

Risk factors of severe COVID-19: a review of host, viral and environmental factors

L Zsichla, V Müller - Viruses, 2023 - mdpi.com
The clinical course and outcome of COVID-19 are highly variable, ranging from
asymptomatic infections to severe disease and death. Understanding the risk factors of …

[PDF][PDF] 12, 13-diHOME: an exercise-induced lipokine that increases skeletal muscle fatty acid uptake

KI Stanford, MD Lynes, H Takahashi, LA Baer, PJ Arts… - Cell metabolism, 2018 - cell.com
Circulating factors released from tissues during exercise have been hypothesized to
mediate some of the health benefits of regular physical activity. Lipokines are circulating …

Cinnamaldehyde in diabetes: A review of pharmacology, pharmacokinetics and safety

R Zhu, H Liu, C Liu, L Wang, R Ma, B Chen, L Li… - Pharmacological …, 2017 - Elsevier
Cinnamaldehyde, one of the active components derived from Cinnamon, has been used as
a natural flavorant and fragrance agent in kitchen and industry. Emerging studies have been …

[PDF][PDF] Adenosine/A2B receptor signaling ameliorates the effects of aging and counteracts obesity

T Gnad, G Navarro, M Lahesmaa, L Reverte-Salisa… - Cell metabolism, 2020 - cell.com
The combination of aging populations with the obesity pandemic results in an alarming rise
in non-communicable diseases. Here, we show that the enigmatic adenosine A2B receptor …

[HTML][HTML] Human adipose beiging in response to cold and mirabegron

BS Finlin, H Memetimin, AL Confides, I Kasza, B Zhu… - JCI insight, 2018 - ncbi.nlm.nih.gov
BACKGROUND. The induction of beige adipocytes in sc white adipose tissue (WAT) depots
of humans is postulated to improve glucose and lipid metabolism in obesity. The ability of …

[HTML][HTML] Effect of exercise on fatty acid metabolism and adipokine secretion in adipose tissue

A Mika, F Macaluso, R Barone, V Di Felice… - Frontiers in …, 2019 - frontiersin.org
Increased physical activity is an optimal way to maintain a good health. During exercise,
triacylglycerols, an energy reservoir in adipose tissue, are hydrolyzed to free fatty acids …