Skeletal muscle-fat interaction is essential for maintaining organismal energy homeostasis
and managing obesity by secreting cytokines and exosomes, but the role of the latter as a …

Endurance exercise training induces adaptations in metabolically active organs, but
adaptations in human subcutaneous adipose tissue (scAT) remains incompletely …

The aim of the present work was to further explore the physiological roles of muscle-derived
IL-6. Adult-floxed and conditional skeletal muscle IL-6 knock out male and female mice were …

The menopause transition is a period associated with changes in body weight and
composition and fat distribution. Women transitioning through the menopause experience a …

Abstract Purpose of Review To summarize the state-of-the-art regarding the exercise-
regulated endocrine signals that might modulate brown adipose tissue (BAT) activity and/or …

Aerobic exercise training (AER) may promote several adaptations in white adipose tissue
(WAT), including a phenotypic change known as browning. The present study aimed at …

Channeling carbohydrates and fatty acids to thermogenic tissues, including brown and
beige adipocytes, have garnered interest as an approach for the management of obesity …

Exercise enhances insulin sensitivity; it also improves adipocyte metabolism and reduces
adipose tissue inflammation through poorly defined mechanisms. Fibroblast growth factor 21 …

The hypothesis linking hyperactivity with weight loss associated hypoleptinemia in anorexia
nervosa gained momentum after a study showing that leptin suppressed semi-starvation …

Adipose tissue accumulation is an independent and modifiable risk factor for cardiovascular
disease (CVD). The recent CVD European Guidelines strongly recommend regular physical …