Stimulus-controlled anion binding and transport by synthetic receptors

J de Jong, JE Bos, SJ Wezenberg - Chemical Reviews, 2023 - ACS Publications
Anionic species are omnipresent and involved in many important biological processes. A
large number of artificial anion receptors has therefore been developed. Some of these are …

Biological applications of synthetic anion transporters

N Akhtar, O Biswas, D Manna - Chemical Communications, 2020 - pubs.rsc.org
The use of synthetic ion transporters for alteration of the concentration of ions across cell
membranes has drawn attention from scientists over the last two decades. This ion transport …

Quinoline thiourea-based zinc ionophores with antibacterial activity

S Dey, A Patel, N Haloi, S Srimayee… - Journal of Medicinal …, 2023 - ACS Publications
The increasing resistance of bacteria to commercially available antibiotics threatens patient
safety in healthcare settings. Perturbation of ion homeostasis has emerged as a potential …

Antifungal exploration of quinoline derivatives against phytopathogenic fungi inspired by quinine alkaloids

YJ Chen, KY Ma, SS Du, ZJ Zhang, TL Wu… - Journal of Agricultural …, 2021 - ACS Publications
Enlightened from our previous work of structural simplification of quinine and innovative
application of natural products against phytopathogenic fungi, lead structure 2, 8-bis …

Antibacterial, antiviral, and antifungal activities of quinine and its derivatives: A narrative mini-review

MR Mohammadi, E Rezaei Niaraki - Micro Nano Bio Aspects, 2023 - mnba-journal.com
Quinine sulfate, the main active compound from quinine extract, has been applied as an old
drug under the category of a limited over-the-counter drug. This compound is a medication …

Recent advances in bioactive artificial ionophores

A Roy, P Talukdar - ChemBioChem, 2021 - Wiley Online Library
Several life‐threatening diseases, also known as 'Channelopathies' are linked to
irregularities in ion transport proteins. Significant research efforts have fostered the …

[HTML][HTML] Determination of quinine in tonic water at the miniaturized and polarized liquid–liquid interface

K Rudnicki, K Sobczak, P Borgul, S Skrzypek… - Food Chemistry, 2021 - Elsevier
In this work we report an electrochemical approach to quantitative and qualitative analysis of
quinine (QN) at the interface between two immiscible electrolyte solutions (ITIES). This was …

[HTML][HTML] Cytotoxicity of cinchona alkaloid organocatalysts against MES-SA and MES-SA/Dx5 multidrug-resistant uterine sarcoma cell lines

SP Pósa, G Dargó, S Nagy, P Kisszékelyi… - Bioorganic & Medicinal …, 2022 - Elsevier
Since the first application of natural quinine as an anti-malarial drug, cinchona alkaloids and
their derivatives have been exhaustively studied for their biological activity. In our work, we …

A potent ion channel blocker, hydroquinidine, exhibits strong anti-cancer activity on colon, pancreatic, and hepatocellular cancer cells

M Yavuz, T Demircan - Molecular Biology Reports, 2023 - Springer
Background Despite recent advances in drug discovery, cancer is still one of the most lethal
health problems worldwide. In most cases, standard therapy methods and multi-modal …

Light-Driven Photoconversion of Squaramides with Implications in Anion Transport

M Vega, L Martínez-Crespo, M Barceló-Oliver… - Organic …, 2023 - ACS Publications
Simple, clean and fast photoconversion of aniline-derived squaramides was achieved by
flashlight illumination. UV irradiation enabled the photochemical squaramide ring-opening …