[HTML][HTML] An overview of descriptors to capture protein properties–Tools and perspectives in the context of QSAR modeling
J Emonts, JF Buyel - Computational and Structural Biotechnology Journal, 2023 - Elsevier
Proteins are important ingredients in food and feed, they are the active components of many
pharmaceutical products, and they are necessary, in the form of enzymes, for the success of …
pharmaceutical products, and they are necessary, in the form of enzymes, for the success of …
Chemical and biological conjugation strategies for the development of multivalent protein vaccine nanoparticles
The development of subunit vaccine platforms has been of considerable interest due to their
good safety profile and ability to be adapted to new antigens, compared to other vaccine …
good safety profile and ability to be adapted to new antigens, compared to other vaccine …
[HTML][HTML] Developing an efficient MGCR microneedle nanovaccine patch for eliciting th 1 cellular response against the SARS-CoV-2 infection
A Gao, Y Chen, H Liang, X Cui, A Zhang, D Cui - Theranostics, 2023 - ncbi.nlm.nih.gov
Abstract Rationale: Novel vaccine R&D is essential to interrupt the COVID-19 pandemic and
other epidemics in the future. Subunit vaccines have received tremendous attention for their …
other epidemics in the future. Subunit vaccines have received tremendous attention for their …
[HTML][HTML] Durability and cross-reactivity of immune responses induced by a plant-based virus-like particle vaccine for COVID-19
P Gobeil, S Pillet, I Boulay, N Charland, A Lorin… - Nature …, 2022 - nature.com
As the SARS-CoV-2 pandemic evolves, vaccine evaluation needs to include consideration
of both durability and cross-reactivity. This report expands on previously reported results …
of both durability and cross-reactivity. This report expands on previously reported results …
Design, optimization, production and activity testing of recombinant immunotoxins expressed in plants and plant cells for the treatment of monocytic leukemia
M Knödler, K Frank, L Kerpen, JF Buyel - Bioengineered, 2023 - Taylor & Francis
Antibody–drug conjugates (ADCs) can improve therapeutic indices compared to plain
monoclonal antibodies (mAbs). However, ADC synthesis is complex because the …
monoclonal antibodies (mAbs). However, ADC synthesis is complex because the …
DNA Delivery by Virus-Like Nanocarriers in Plant Cells
MR Islam, M Youngblood, HI Kim… - Nano Letters, 2024 - ACS Publications
Tobacco mild green mosaic virus (TMGMV)-like nanocarriers were designed for gene
delivery to plant cells. High aspect ratio TMGMVs were coated with a polycationic …
delivery to plant cells. High aspect ratio TMGMVs were coated with a polycationic …
[HTML][HTML] Current advances of plant-based vaccines for neurodegenerative diseases
LA Bravo-Vázquez, EO Mora-Hernández… - Pharmaceutics, 2023 - mdpi.com
Neurodegenerative diseases (NDDs) are characterized by the progressive degeneration
and/or loss of neurons belonging to the central nervous system, and represent one of the …
and/or loss of neurons belonging to the central nervous system, and represent one of the …
[HTML][HTML] Virus-like particles (VLPs)-based vaccines against COVID-19: Where do we stand amid the ongoing evolution of SARS-CoV-2?
The causative agent of the COVID-19 pandemic is undergoing several changes, and the
evolutionary cascade of SARS-CoV-2 has led to the emergence of a range of variants of …
evolutionary cascade of SARS-CoV-2 has led to the emergence of a range of variants of …
Safety and immunogenicity of a modified COVID-19 mRNA vaccine, SYS6006, as a fourth-dose booster following three doses of inactivated vaccines in healthy adults …
Y Gui, Y Cao, J He, C Zhao, W Zheng, L Qian… - Life …, 2023 - academic.oup.com
The continuous emergence of the severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) variants led to a rapid decline in protection efficacy and neutralizing titers even after …
CoV-2) variants led to a rapid decline in protection efficacy and neutralizing titers even after …
To be remembered: B cell memory response against SARS‐CoV‐2 and its variants in vaccinated and unvaccinated individuals
N Ahmed, A Athavale, AH Tripathi… - Scandinavian …, 2024 - Wiley Online Library
COVID‐19 disease has plagued the world economy and affected the overall well‐being and
life of most of the people. Natural infection as well as vaccination leads to the development …
life of most of the people. Natural infection as well as vaccination leads to the development …