Does general anesthesia affect neurodevelopment in infants and children?

ME McCann, SG Soriano - Bmj, 2019 - bmj.com
General anesthesia has been unequivocally linked to abnormal development of the central
nervous system, leading to neurocognitive impairments in laboratory models. In vitro and in …

Clinical evidence for any effect of anesthesia on the developing brain

AJ Davidson, LS Sun - Anesthesiology, 2018 - pubs.asahq.org
A recent US Food and Drug Administration warning advised that prolonged or repeated
exposure to general anesthetics may affect neurodevelopment in children. This warning is …

Update on developmental anesthesia neurotoxicity

L Vutskits, A Davidson - Current Opinion in Anesthesiology, 2017 - journals.lww.com
Experimental data with reasonable translational relevance suggest that early-life exposure
to general anesthetics can induce lasting behavioral and cognitive deficits. In contrast …

Neurodevelopmental outcome of patients with congenital gastrointestinal malformations: a systematic review and meta-analysis

D Roorda, M Königs, LE Schattenkerk… - Archives of Disease in …, 2021 - fn.bmj.com
Aim Children with congenital gastrointestinal malformations may be at risk of
neurodevelopmental impairment due to challenges to the developing brain, including …

Contemporary outcomes of the Foker process and evolution of treatment algorithms for long-gap esophageal atresia

WJ Svetanoff, B Zendejas, K Hernandez… - Journal of pediatric …, 2021 - Elsevier
Background Esophageal growth using the Foker process (FP) for long-gap esophageal
atresia (LGEA) has evolved over time. Methods Contemporary LGEA patients treated from …

The new FDA drug safety communication on the use of general anesthetics in young children: what should we make of it?

A Davidson, L Vutskits - Paediatric anaesthesia, 2017 - europepmc.org
The new FDA drug safety communication on the use of general anesthetics in young children:
what should we make of it? - Abstract - Europe PMC Sign in | Create an account https://orcid.org …

Prenatal propofol exposure downregulates NMDA receptor expression and causes cognitive and emotional disorders in rats

D Chen, X Qi, R Zhuang, J Cao, Y Xu, X Huang… - European Journal of …, 2019 - Elsevier
The impacts of prenatal propofol on cognition and emotion of offspring remain elusive. In the
present study, pregnant rats in the second trimester were anesthetized with propofol …

[HTML][HTML] Early neurodevelopmental outcomes of congenital gastrointestinal surgical conditions: a single-centre retrospective study

V Batta, S Rao, D Wagh, JKG Tan, I Gollow… - BMJ paediatrics …, 2020 - ncbi.nlm.nih.gov
Background Evidence is emerging that surgery in the neonatal period is associated with
increased risk of suboptimal neurodevelopmental outcomes (SNDO). The aim of this study …