Top advances of the year: Leukemia
A Kent, DA Pollyea - Cancer, 2023 - Wiley Online Library
In the year 2021, there were three new Food and Drug Administration approvals for all
leukemia types: asciminib (Scemblix) for chronic myeloid leukemia, brexucabtagene …
leukemia types: asciminib (Scemblix) for chronic myeloid leukemia, brexucabtagene …
Combination of a New Oral Demethylating Agent, OR2100, and Venetoclax for Treatment of Acute Myeloid Leukemia
K Kamachi, H Ureshino, T Watanabe… - Cancer Research …, 2023 - AACR
The standard treatment for elderly patients with acute myeloid leukemia (AML) is venetoclax
(Ven), a BCL-2–selective inhibitor, combined with hypomethylating agents (HMA) such as …
(Ven), a BCL-2–selective inhibitor, combined with hypomethylating agents (HMA) such as …
Real-world outcomes of newly diagnosed AML treated with venetoclax and azacitidine or low-dose cytarabine in the UK NHS
Venetoclax with azacitidine is the standard of care for patients with AML who are unfit for
intensive chemotherapy, however uncertainties remain regarding the treatment schedule …
intensive chemotherapy, however uncertainties remain regarding the treatment schedule …
Epigenetic targeted therapies in hematological malignancies
D Venney, G Greenfield, P Preston… - Epigenetic Cancer …, 2023 - Elsevier
Malignancy can arise in many forms in the hematopoietic system, affecting both lymphoid
and myeloid cells and causing acute and chronic disorders and affecting all age groups …
and myeloid cells and causing acute and chronic disorders and affecting all age groups …
Methylation of SPRED1: A new target in acute myeloid leukemia
N Su, Y Wang, X Lu, W Xu, H Wang, W Mo… - Frontiers in …, 2022 - frontiersin.org
Sprouty-related, EVH1 domain-containing protein 1 (SPRED1) has been identified as a
novel tumor suppressor gene in acute myeloid leukemia (AML). Previous studies showed …
novel tumor suppressor gene in acute myeloid leukemia (AML). Previous studies showed …
[HTML][HTML] Venetoclax and Cobimetinib in Relapsed/Refractory AML: A Phase 1b Trial
MY Konopleva, M Dail, NG Daver, JS Garcia… - … Myeloma and Leukemia, 2024 - Elsevier
Background Therapies for relapsed/refractory acute myeloid leukemia remain limited and
outcomes poor, especially amongst patients who are ineligible for cytotoxic chemotherapy or …
outcomes poor, especially amongst patients who are ineligible for cytotoxic chemotherapy or …
Significance of gene diagnosis in acute myeloid leukemia with the emergence of new molecular target drug treatment
H Yamaguchi - Journal of Nippon Medical School, 2022 - jstage.jst.go.jp
Department of Hematology, Nippon Medical School, Tokyo, Japan Acute myeloid leukemia
(AML) is a heterogeneous hematopoietic malignancy accompanied by impaired …
(AML) is a heterogeneous hematopoietic malignancy accompanied by impaired …
The increasingly blurred line between induction, consolidation and maintenance in acute myeloid leukaemia
A Frisch, JM Rowe, Y Ofran - British Journal of Haematology, 2023 - Wiley Online Library
Since the early 1970s, the treatment of acute myeloid leukaemia (AML) has undergone a
major transformation. Initially based on only two drugs, an anthracycline and cytosine …
major transformation. Initially based on only two drugs, an anthracycline and cytosine …
[PDF][PDF] 急性髓系白血病患者血小板输注疗效不佳及短期死亡的危险因素分析
许京菁, 周谋, 高飏, 李少文, 朱展鸿… - Progress in …, 2023 - biomed.cnjournals.com
摘要目的: 分析急性髓系白血病(AML) 患者血小板输注疗效不佳及短期死亡的危险因素. 方法:
将2019 年4 月至2021 年1 月期间南部战区总医院收治的97 例AML 患者作为研究对象 …
将2019 年4 月至2021 年1 月期间南部战区总医院收治的97 例AML 患者作为研究对象 …
[HTML][HTML] Updating the American Society of Hematology guidelines for treating older adults with acute myeloid leukemia
RM Stone, JK Altman, MA Sekeres - Blood advances, 2023 - ncbi.nlm.nih.gov
The American Society of Hematology (ASH) 2020 guidelines for treating newly diagnosed
acute myeloid leukemia (AML) in older adults answered 6 critical treatment questions …
acute myeloid leukemia (AML) in older adults answered 6 critical treatment questions …