Insulin resistance (IR) and cardiovascular disease (CVD) represent two universal public
health hazards, especially in today's Western societies. A causal-effect relationship has …

The breakthrough discoveries of leptin and adiponectin more than two decades ago led to a
widespread recognition of adipose tissue as an endocrine organ. Many more adipose tissue …

Nowadays, diabetes and obesity are two main health-threatening metabolic disorders in the
world, which increase the risk for many chronic diseases. Apelin, a peptide hormone, exerts …

The orexin/hypocretin neuropeptide family has emerged as a focal point of neuroscientific
research following the discovery that this family plays a crucial role in a variety of …

Adipocytokines are hormonally active molecules that are believed to play a key role in the
regulation of crucial biological processes in the human body. Numerous experimental …

Apelin is an endogenous ligand of G protein-coupled receptor APJ. It is extensively
expressed in many tissues such as heart, liver, and kidney, especially in lung tissue. A …

It is now established that adipose tissue, skeletal muscle, and heart are endocrine organs
and secrete in normal and in pathological conditions several molecules, called, respectively …

Background The present study was designed to determine whether zinc supplementation
would increase the effects of restricted calorie diet (RCD) on obesity. Methods and materials …

Neurodegenerative diseases (NDs), such as Alzheimer's disease (AD), Parkinson's disease
(PD), Huntington's disease (HD), and amyotrophic lateral sclerosis (ALS), are disorders …

Background and Aims Apelin (APLN) is the endogenous ligand of its G protein–coupled
receptor, apelin receptor (APJ). APLN serum levels are increased in human liver diseases …