The medial temporal lobe (MTL) is connected to the rest of the brain through two main
networks: the anterior-temporal (AT) and the posterior-medial (PM) systems. Given the …

Abstract To move Alzheimer Disease (AD) research forward it is essential to collect data
from large cohorts, but also make such data available to the global research community. We …

Introduction It is unclear how different proteinopathies (tau, transactive response DNA‐
binding protein 43 [TDP‐43], amyloid β [Aβ], and α‐synuclein) contribute to atrophy within …

Obesity is recognized as a significant risk factor for Alzheimer's disease (AD). Studies have
supported that obesity accelerates AD-related pathophysiology and memory impairment in …

Background Plasma amyloid-β (Aβ) levels are increasingly studied as a potential accessible
marker of cognitive impairment and dementia. However, it remains underexplored whether …

The hippocampus is one of the first regions to demonstrate atrophy during the prodromal
stage of Alzheimer's disease. Volumetric analysis of its individual subfields could provide …

Background The human hippocampus comprises a number of interconnected histologically
and functionally distinct subfields, which may be differentially influenced by cerebral …

The purpose of the present review is to provide an update of the available recent scientific
literature on the use of magnetic resonance imaging (MRI) in Alzheimer's disease (AD). MRI …

The hippocampus has been extensively studied in various neuropsychiatric disorders
throughout the lifespan. However, inconsistent results have been reported with respect to …

Background Cognitive composites commonly serve as primary outcomes in Alzheimer's
disease (AD) secondary prevention trials. Objective To evaluate the association between …