[HTML][HTML] Targeting PI3K/AKT signaling for treatment of idiopathic pulmonary fibrosis
J Wang, K Hu, X Cai, B Yang, Q He, J Wang… - … Pharmaceutica Sinica B, 2022 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a chronic progressive fibrotic interstitial pneumonia
with unknown causes. The incidence rate increases year by year and the prognosis is poor …
with unknown causes. The incidence rate increases year by year and the prognosis is poor …
Role of gut microbiota in identification of novel TCM-derived active metabolites
TL Lin, CC Lu, WF Lai, TS Wu, JJ Lu, YM Chen… - Protein & …, 2021 - academic.oup.com
Abstract Traditional Chinese Medicine (TCM) has been extensively used to ameliorate
diseases in Asia for over thousands of years. However, owing to a lack of formal scientific …
diseases in Asia for over thousands of years. However, owing to a lack of formal scientific …
Quercetin attenuates atherosclerotic inflammation by inhibiting galectin‐3‐NLRP3 signaling pathway
H Li, L Xiao, H He, H Zeng, J Liu… - Molecular nutrition & …, 2021 - Wiley Online Library
Scope Atherosclerosis is the underlying pathogenesis of cardiovascular events caused by
inflammation, and dietary intervention has been recommended as one fundamental …
inflammation, and dietary intervention has been recommended as one fundamental …
The important role of polysaccharides from a traditional Chinese medicine-Lung Cleansing and Detoxifying Decoction against the COVID-19 pandemic
P Cao, S Wu, T Wu, Y Deng, Q Zhang, K Wang… - Carbohydrate …, 2020 - Elsevier
The new coronavirus pneumonia, named COVID-19 by the World Health Organization, has
become a pandemic. It is highly pathogenic and reproduces quickly. There are currently no …
become a pandemic. It is highly pathogenic and reproduces quickly. There are currently no …
Cryptotanshinone protects against pulmonary fibrosis through inhibiting Smad and STAT3 signaling pathways
Cryptotanshinone (CTS), a lipophilic compound extracted from root of Salvia miltiorrhiza
(Danshen), has demonstrated multiple pharmacological activities, including anti …
(Danshen), has demonstrated multiple pharmacological activities, including anti …
[HTML][HTML] Lianhua Qingwen prescription for Coronavirus disease 2019 (COVID-19) treatment: Advances and prospects
LC Li, ZH Zhang, WC Zhou, J Chen, HQ Jin… - Biomedicine & …, 2020 - Elsevier
Abstract Background An outbreak of Coronavirus Disease 2019 (COVID-19) which was
infected by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), is still …
infected by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), is still …
[HTML][HTML] Drugs and targets in fibrosis
Fibrosis contributes to the development of many diseases and many target molecules are
involved in fibrosis. Currently, the majority of fibrosis treatment strategies are limited to …
involved in fibrosis. Currently, the majority of fibrosis treatment strategies are limited to …
[HTML][HTML] Indole-based small molecules as potential therapeutic agents for the treatment of fibrosis
R Qin, Q Zhao, B Han, HP Zhu, C Peng… - Frontiers in …, 2022 - frontiersin.org
Indole alkaloids are widely distributed in nature and have been particularly studied because
of their diverse biological activities, such as anti-inflammatory, anti-tumor, anti-bacterial, and …
of their diverse biological activities, such as anti-inflammatory, anti-tumor, anti-bacterial, and …
Therapeutic potential of traditional Chinese medicine for interstitial lung disease
YM Zhou, XR Dong, D Xu, J Tang, YL Cui - Journal of Ethnopharmacology, 2023 - Elsevier
Ethnopharmacological relevance Interstitial lung disease (ILD) is a chronic lung dysfunction
disease with a poor prognosis and poor recovery. The clinically used therapeutic drugs …
disease with a poor prognosis and poor recovery. The clinically used therapeutic drugs …
[HTML][HTML] Hyperoside attenuates bleomycin-induced pulmonary fibrosis development in mice
J Huang, X Tong, L Zhang, Y Zhang, L Wang… - Frontiers in …, 2020 - frontiersin.org
Idiopathic pulmonary fibrosis (IPF) is a progressive, lethal, and chronic lung disease. There
are no effective drug therapies for IPF. Hyperoside, a flavonoid glycoside, has been proven …
are no effective drug therapies for IPF. Hyperoside, a flavonoid glycoside, has been proven …