Development strategies of polymorphs and solvates for enhancing powder properties: A case study of thiothiamine

R Han, H Qu, Y Li, Y Liu, T Tao, W Tang… - Crystal Growth & …, 2023 - ACS Publications
Crystals with an acicular shape are a “nightmare” to many chemical engineers due to their
poor powder properties, posing numerous challenges in purification, filtration, washing, and …

Spironolactone: New Polymorphic Form III and Revisiting Form II at Low Temperatures

C Golz, A Krawczuk - Crystal Growth & Design, 2023 - ACS Publications
The steroidal drug spironolactone is known for its propensity to form many polymorphs and
solvate forms that are governed by dispersive interactions and hence is a subject of interest …

Isostructurality or Not: A Deep Insight into the Selective Formation of Spironolactone Solvates

L Jia, JYY Heng, P Cui, L Zhou, Q Yin - Crystal Growth & Design, 2023 - ACS Publications
Isostructurality is a potential tool to design crystals with tailored arrangements, especially for
multicomponent systems, but research into its formation mechanism is still limited to date …

Weak but Vital: The Role of Solvents in Crystal Packing and Coassembly for the Formation of Multicomponent Salt Solvates of Clozapine with Oxalic Acid

C Li, C Zhang, H Wang, W Chen - Crystal Growth & Design, 2024 - ACS Publications
In order to explore the role of solvent molecules (acetonitrile and ethanol) in crystal packing
and coassembly for the formation of three multicomponent salt solvates of clozapine (CLZ) …

Discovery and exploration of new solid forms of dipeptide: l-alanyl-l-glutamine

J Fu, M Cai, Y Shi, Y Hou, R Guo, C Wang, J Zhao… - …, 2024 - pubs.rsc.org
L-Alanyl-L-glutamine (Ala–Gln) is a dipeptide which is widely used in medical and nutritional
fields. Two new crystalline forms (form III and form IV) and a DMSO solvate form (SDMSO) of …