The treatment of differentiated thyroid cancer in children: emphasis on surgical approach and radioactive iodine therapy

SA Rivkees, EL Mazzaferri, FA Verburg… - Endocrine …, 2011 - academic.oup.com
Pediatric thyroid cancer is a rare disease with an excellent prognosis. Compared with adults,
epithelial-derived differentiated thyroid cancer (DTC), which includes papillary and follicular …

MicroRNA signature distinguishes the degree of aggressiveness of papillary thyroid carcinoma

L Yip, L Kelly, Y Shuai, MJ Armstrong… - Annals of surgical …, 2011 - Springer
Background Papillary thyroid carcinoma (PTC) has relatively indolent behavior, although
some tumors recur and disseminate to distant sites. The aggressive biological behavior of …

Enhancer remodeling during adaptive bypass to MEK inhibition is attenuated by pharmacologic targeting of the P-TEFb complex

JS Zawistowski, SM Bevill, DR Goulet, TJ Stuhlmiller… - Cancer discovery, 2017 - AACR
Targeting the dysregulated BRAF–MEK–ERK pathway in cancer has increasingly emerged
in clinical trial design. Despite clinical responses in specific cancers using inhibitors …

miR-146b is Highly Expressed in Adult Papillary Thyroid Carcinomas with High Risk Features Including Extrathyroidal Invasion and the BRAFV600E Mutation

CK Chou, RF Chen, FF Chou, HW Chang, YJ Chen… - Thyroid, 2010 - liebertpub.com
Background: Papillary thyroid carcinoma (PTC) are clinicopathogenetically heterogeneous.
Micro-RNAs (miRNAs) are involved in the pathogenesis of diverse human cancers …

Association of High Iodine Intake with the T1799A BRAF Mutation in Papillary Thyroid Cancer

H Guan, M Ji, R Bao, H Yu, Y Wang… - The Journal of …, 2009 - academic.oup.com
Context: Epidemiological studies have indicated that high iodine intake might be a risk factor
for papillary thyroid cancer (PTC), which commonly harbors the oncogenic T1799A BRAF …

Subclinical lymph node metastasis in papillary thyroid microcarcinoma: a study of 551 resections

YK So, YI Son, SD Hong, MY Seo, CH Baek, HS Jeong… - Surgery, 2010 - Elsevier
BACKGROUND: In clinically node-negative papillary thyroid microcarcinoma (PTMC), the
frequency of subclinical lymph node metastasis (LNM) in the central cervical compartment …

Nomogram based on shear-wave elastography radiomics can improve preoperative cervical lymph node staging for papillary thyroid carcinoma

M Jiang, C Li, S Tang, W Lv, A Yi, B Wang, S Yu, X Cui… - Thyroid, 2020 - liebertpub.com
Background: Accurate preoperative prediction of cervical lymph node (LN) metastasis in
patients with papillary thyroid carcinoma (PTC) provides a basis for surgical decision …

Prognostic utility of BRAF mutation in papillary thyroid cancer

M Xing - Molecular and cellular endocrinology, 2010 - Elsevier
Papillary thyroid cancer (PTC) is a common endocrine malignancy that frequently harbors
the oncogenic T1799A BRAF mutation. As a novel prognostic molecular marker, this …

[HTML][HTML] Identification of ferroptosis genes in immune infiltration and prognosis in thyroid papillary carcinoma using network analysis

R Lin, CE Fogarty, B Ma, H Li, G Ni, X Liu, J Yuan… - BMC genomics, 2021 - Springer
Background Papillary thyroid carcinoma (PTC) is the most common thyroid cancer. While
many patients survive, a portion of PTC cases display high aggressiveness and even …

[PDF][PDF] BRAF (V600E) mutation and the biology of papillary thyroid cancer

F Frasca, C Nucera, G Pellegriti, P Gangemi… - Endocrine-related …, 2008 - academia.edu
Abstract BRAF (V600E) mutation is the most frequent genetic alteration in papillary thyroid
carcinomas (PTCs) that are 80–90% of all thyroid cancers. We evaluated the relationship …