The aim of this study is to search for relationships between histology, radioiodine (131 I)
uptake, fluorodeoxyglucose (FDG) uptake, and disease outcome in patients with metastatic …

Purpose For the past 65 years, patient age at diagnosis has been widely used as a major
mortality risk factor in the risk stratification of papillary thyroid cancer (PTC), but whether this …

A number of histologic variants of well‐differentiated papillary carcinoma have been found to
be associated with more aggressive tumor behavior. Tall cell, columnar cell, diffuse …

Thyroid cancer is an increasingly prevalent malignancy throughout the world. Management
guidelines for both thyroid nodules and thyroid cancer have been published and updated by …

Background: Thyroid nodules are a common clinical problem, and differentiated thyroid
cancer is becoming increasingly prevalent. Since the American Thyroid Association's …

Although B-RafV600E is the most common somatic mutation in papillary thyroid carcinoma
(PTC), how it induces tumor aggressiveness is not fully understood. Using gene set …

The central role of the BRAF–MEK–ERK pathway in controlling cell fate has made this
pathway a primary target for deregulated activation in cancer. BRaf is activated by Ras …

BRAF, a cytoplasmic serine–threonine protein kinase, plays a critical role in cell signaling as
an activator within the mitogen-activated protein kinase (MAPK) pathway. The most common …

Background: Anaplastic thyroid carcinoma (ATC) is a rare tumor, with poorly defined
oncogenic molecular mechanisms and limited therapeutic options contributing to its poor …

Background: There remain a small number of patients with papillary thyroid cancer (PTC)
who suffer recurrence, metastases, or death. While mutation of the BRAF gene …