MicroRNA-146b: a novel biomarker and therapeutic target for human papillary thyroid cancer

CK Chou, RT Liu, HY Kang - International journal of molecular sciences, 2017 - mdpi.com
Papillary thyroid cancer (PTC) is the most common tumor subtype of thyroid cancer.
However, not all PTCs are responsive to current surgical and radioiodine treatment. The well …

Predictive factors for lymph node metastasis in papillary thyroid microcarcinoma

SK Kim, I Park, JW Woo, JH Lee, JH Choe… - Annals of surgical …, 2016 - Springer
Background Because lymph node (LN) metastasis has been proven to be a predictor for
locoregional recurrence (LRR) in papillary thyroid microcarcinoma (PTMC), better …

A High Percentage of BRAFV600E Alleles in Papillary Thyroid Carcinoma Predicts a Poorer Outcome

A Guerra, L Fugazzola, V Marotta… - The Journal of …, 2012 - academic.oup.com
Context: BRAFV600E is considered a negative prognostic marker in papillary thyroid
carcinoma (PTC), but unexplained conflicting results are present in the literature. In light of …

Histopathologic and Clinical Characterization of Thyroid Tumors Carrying the BRAFK601E Mutation

M Afkhami, A Karunamurthy, S Chiosea, MN Nikiforova… - Thyroid, 2016 - liebertpub.com
Background: While the association of the BRAFV600E mutation with aggressive
histopathological tumor features and clinical behavior has been extensively studied in …

[HTML][HTML] Signaling pathways in thyroid cancer and their therapeutic implications

S Jin, O Borkhuu, W Bao, YT Yang - Journal of clinical medicine …, 2016 - ncbi.nlm.nih.gov
Thyroid cancer is a common malignancy of endocrine system, and has now become the
fastest increasing cancer among all the malignancies. The development, progression …

The role of molecular testing for the indeterminate thyroid FNA

ED Rossi, L Pantanowitz, WC Faquin - Genes, 2019 - mdpi.com
Thyroid nodules are common in the adult population where a majority are benign and only
4.0% to 6.5% are malignant. Fine needle aspiration (FNA) is a key method used in the early …

Induction of thyroid gene expression and radioiodine uptake in thyroid cancer cells by targeting major signaling pathways

P Hou, E Bojdani, M Xing - The Journal of Clinical …, 2010 - academic.oup.com
Context: Radioiodine ablation is commonly used to treat thyroid cancer, but a major
challenge is often the loss of radioiodine avidity of the cancer caused by aberrant silencing …

Clinicopathologic Implications of the BRAFV600E Mutation in Papillary Thyroid Cancer: A Subgroup Analysis of 3130 Cases in a Single Center

JY Lim, SW Hong, YS Lee, BW Kim, CS Park… - Thyroid, 2013 - liebertpub.com
Background: The BRAF mutation has been shown to be associated with aggressive
clinicopathologic characteristics of papillary thyroid cancer (PTC). However, several studies …

Artificial intelligence to predict the BRAFV600E mutation in patients with thyroid cancer

J Yoon, E Lee, JS Koo, JH Yoon, KH Nam, J Lee… - PloS one, 2020 - journals.plos.org
Purpose To investigate whether a computer-aided diagnosis (CAD) program developed
using the deep learning convolutional neural network (CNN) on neck US images can predict …

Clinical significance and diagnostic value of QPCT, SCEL and TNFRSF12A in papillary thyroid cancer

T Liang, X Wu, L Wang, Z Ni, Y Fan, P Wu… - … -Research and Practice, 2023 - Elsevier
Purpose To identify specific novel genes that could be used as diagnostic and prognostic
factors in papillary thyroid carcinoma (PTC). Methods Screening of differential genes by …