Medulloblastoma (MB) is the most common malignant brain tumor in children. There
remains an unmet need for diagnostics to sensitively detect the disease, particularly …

Posterior fossa ependymoma comprise three distinct molecular variants, termed PF-EPN-A
(PFA), PF-EPN-B (PFB), and PF-EPN-SE (subependymoma). Clinically, they are very …

Despite advances in treatment regimens that comprise surgery, chemotherapy, and
radiation, outcome of many brain tumors remains dismal, more so when they recur. The …

In 2016, medulloblastoma classification was restructured to allow for incorporation of
updated data about medulloblastoma biology, genomics, and clinical behavior. For the first …

BACKGROUND AND PURPOSE: Distinct molecular subgroups of pediatric
medulloblastoma confer important differences in prognosis and therapy. Currently, tissue …

Background Clustering algorithms with steps involving randomness usually give different
results on different executions for the same dataset. This non-deterministic nature of …

How abnormal neurodevelopment relates to the tumour aggressiveness of medulloblastoma
(MB), the most common type of embryonal tumour, remains elusive. Here we uncover a …

Co-pollution of antibiotics and metals is prevailing in aquatic environments. However, risks
of coexisted antibiotics and metals on aquatic organisms is unclear. This study investigated …

Medulloblastoma, which is the most common malignant paediatric brain tumour, has a 70%
survival rate, but standard treatments often lead to devastating life-long side effects and …

Background Most children with medulloblastoma fall within the standard-risk clinical disease
group defined by absence of high-risk features (metastatic disease, large-cell/anaplastic …