Preclinical Absorption, Distribution, Metabolism, and Excretion of Sodium Danshensu, One of the Main Water-Soluble Ingredients in Salvia miltiorrhiza, in Rats

X Meng, J Jiang, H Pan, S Wu, S Wang… - Frontiers in …, 2019 - frontiersin.org
In this study, the absorption, distribution, metabolism and excretion (ADME) of sodium
danshensu (Sodium DL-β-(3, 4-dihydroxyphenyl) lactate), one of the main water-soluble …

High-throughput determination of sodium danshensu in beagle dogs by the LCMS/MS method, employing liquid-liquid extraction based on 96-well format plates

J Jiang, X Zhao, X Li, S Wu, S Yu, Y Lou, G Fan - Molecules, 2017 - mdpi.com
Sodium Danshensu (sodium d-(+)-β-(3, 4-dihydroxyphenyl) lactate), one of the water-
soluble ingredients in Salvia miltiorrhiza, exhibits potent relaxation of the coronary artery …

Recent advances in the methodology and application for the metabolism of phytochemical compounds-an update covering the period of 2009-2014

W Cao, L Yi, J Cao, SS Hu, P Li - Current Drug Metabolism, 2014 - ingentaconnect.com
The research of drug metabolism is essential for successful drug discovery. Phytochemicals,
particularly those from herbal medicines, have the potential to affect diseases such as …

Development of a high resolution mass spectrometry method for the determination of danshensu and salvianolic acid B

H Zhao, W Zhao - SN Applied Sciences, 2019 - Springer
In this work, a highly sensitive ultrahigh-performance liquid chromatography and quadrupole
Orbitrap high-resolution mass spectrometry (UHPLC-Q-Orbitrap HRMS) method has been …