The mitochondrial oxidative phosphorylation system is central to cellular metabolism. It
comprises five enzymatic complexes and two mobile electron carriers that work in a …

Mitochondria are well known as organelles responsible for the maintenance of cellular
bioenergetics through the production of ATP. Although oxidative phosphorylation may be …

Up to now, a total of 24 succinate dehydrogenase inhibitors (SDHIs) fungicides have been
commercialized, and SDHIs fungicides were also one of the most active fungicides …

The assembly of mitochondrial oxidative phosphorylation (OXPHOS) complexes is an
intricate process, which—given their dual-genetic control—requires tight co-regulation of two …

Human complex II is a key protein complex that links two essential energy-producing
processes: the tricarboxylic acid cycle and oxidative phosphorylation. Deficiencies due to …

Reactive oxygen species (ROS) are unstable reactive molecules that are toxic to cells.
Regulation of ROS homeostasis is crucial to protect cells from dysfunction, senescence, and …

Succinate dehydrogenase, which is known as mitochondrial complex II, has proven to be a
fascinating machinery, attracting renewed and increased interest in its involvement in …

Genetic variation is the major mechanism behind adaptation and evolutionary change. As
most proteins operate through interactions with other proteins, changes in protein complex …

African trypanosomes are dixenous eukaryotic parasites that impose a significant human
and veterinary disease burden on sub-Saharan Africa. Diversity between species and life …

The genetic landscape of pituitary adenomas (PAs) is diverse and many of the identified
cases remain of unclear pathogenetic mechanism. Germline genetic defects account for a …