Centromeres are the chromosomal domains required to ensure faithful transmission of the
genome during cell division. They have a central role in preventing aneuploidy, by …

Satellite DNAs are now regarded as powerful and active contributors to genomic and
chromosomal evolution. Paired with mobile transposable elements, these repetitive …

Centromeres are essential for ensuring proper chromosome segregation in eukaryotes.
Their definition relies on the presence of a centromere-specific H3 histone variant CenH3 …

The centromere is a chromosomal locus responsible for the faithful segregation of genetic
material during cell division. It has become evident that centromeres can be established …

Animal and plant centromeres are embedded in repetitive “satellite” DNA, but are thought to
be epigenetically specified. To define genetic characteristics of centromeres, we surveyed …

Most histones are assembled into nucleosomes during replication to package genomic
DNA. However, several variant histones are deposited independently of replication at …

Maintenance of an intact genome is essential for cellular and organismal homeostasis. The
centromere is a specialized chromosomal locus required for faithful genome inheritance at …

Background Supernumerary chromosomes have been found in many organisms. In fungi,
these “accessory” or “dispensable” chromosomes are present at different frequencies in …

Recently interest in multi-generational epigenetic phenomena have been fuelled by highly
reproducible intergenerational and transgenerational inheritance paradigms in several …

Centromeres are the basic unit for chromosome inheritance, but their evolutionary dynamics
is poorly understood. We generate high-quality reference genomes for multiple Drosophila …