Microfluidics for drug development: from synthesis to evaluation

Y Liu, L Sun, H Zhang, L Shang, Y Zhao - Chemical reviews, 2021 - ACS Publications
Drug development is a long process whose main content includes drug synthesis, drug
delivery, and drug evaluation. Compared with conventional drug development procedures …

Retracted Article: Droplet microfluidics: fundamentals and its advanced applications

S Sohrabi, MK Moraveji - RSC advances, 2020 - pubs.rsc.org
Droplet-based microfluidic systems have been shown to be compatible with many chemical
and biological reagents and capable of performing a variety of operations that can be …

Droplet microfluidics

SY Teh, R Lin, LH Hung, AP Lee - Lab on a Chip, 2008 - pubs.rsc.org
Droplet-based microfluidic systems have been shown to be compatible with many chemical
and biological reagents and capable of performing a variety of “digital fluidic” operations that …

AI on a chip

A Isozaki, J Harmon, Y Zhou, S Li, Y Nakagawa… - Lab on a Chip, 2020 - pubs.rsc.org
Artificial intelligence (AI) has dramatically changed the landscape of science, industry,
defence, and medicine in the last several years. Supported by considerably enhanced …

Fundamentals of microfluidic cell culture in controlled microenvironments

EWK Young, DJ Beebe - Chemical Society Reviews, 2010 - pubs.rsc.org
Microfluidics has the potential to revolutionize the way we approach cell biology research.
The dimensions of microfluidic channels are well suited to the physical scale of biological …

Microfluidic applications of magnetic particles for biological analysis and catalysis

MAM Gijs, F Lacharme, U Lehmann - Chemical reviews, 2010 - ACS Publications
Since the introduction of the concept of Micro Total Analysis System or µTAS in 1990, 1 the
interest in and impact of such devices, also called lab-on-a-chip or miniaturized analysis …

Characterization of cell viability during bioprinting processes

K Nair, M Gandhi, S Khalil, KC Yan… - Biotechnology …, 2009 - Wiley Online Library
Bioprinting is an emerging technology in the field of tissue engineering and regenerative
medicine. The process consists of simultaneous deposition of cells, biomaterial and/or …

Effects of dispensing pressure and nozzle diameter on cell survival from solid freeform fabrication–based direct cell writing

R Chang, JAE Nam, WEI Sun - Tissue Engineering Part A, 2008 - liebertpub.com
Novel technologies are emerging that incorporate cells as part of the building blocks for
various biomanufacturing processes, such as solid freeform fabricated tissue constructs for …

Microfluidic approaches for cancer cell detection, characterization, and separation

J Chen, J Li, Y Sun - Lab on a Chip, 2012 - pubs.rsc.org
This article reviews the recent developments in microfluidic technologies for in vitro cancer
diagnosis. We summarize the working principles and experimental results of key microfluidic …

Single cell optical imaging and spectroscopy

AS Stender, K Marchuk, C Liu, S Sander… - Chemical …, 2013 - ACS Publications
In his 1665 treatise, Micrographia, Robert Hooke described the many observations he had
made using a microscope, including compartment-like structures in cork samples that he …