International consensus statement on obstructive sleep apnea

JL Chang, AN Goldberg, JA Alt… - International forum of …, 2023 - Wiley Online Library
Background Evaluation and interpretation of the literature on obstructive sleep apnea (OSA)
allows for consolidation and determination of the key factors important for clinical …

Acute vs. chronic vs. cyclic hypoxia: their differential dynamics, molecular mechanisms, and effects on tumor progression

K Saxena, MK Jolly - Biomolecules, 2019 - mdpi.com
Hypoxia has been shown to increase the aggressiveness and severity of tumor progression.
Along with chronic and acute hypoxic regions, solid tumors contain regions of cycling …

Hypoxia, oxidative stress, and immune evasion: a trinity of the trichothecenes T-2 toxin and deoxynivalenol (DON)

L You, Y Zhao, K Kuca, X Wang, P Oleksak… - Archives of …, 2021 - Springer
T-2 toxin and deoxynivalenol (DON) are type A and B trichothecenes, respectively. They
widely occur as pollutants in food and crops and cause a series of toxicities, including …

Sleep apnoea adverse effects on cancer: true, false, or too many confounders?

D Gozal, I Almendros, AI Phipps… - International journal of …, 2020 - mdpi.com
Obstructive sleep apnoea (OSA) is a prevalent disorder associated with increased
cardiovascular, metabolic and neurocognitive morbidity. Recently, an increasing number of …

The role of PD-L1 in the immune dysfunction that mediates hypoxia-induced multiple organ injury

Y Sun, J Tan, Y Miao, Q Zhang - Cell Communication and Signaling, 2021 - Springer
Hypoxia is a pathological condition common to many diseases, although multiple organ
injuries induced by hypoxia are often overlooked. There is increasing evidence to suggest …

Hypoxia in lung cancer management: a translational approach

J Ancel, JM Perotin, M Dewolf, C Launois, P Mulette… - Cancers, 2021 - mdpi.com
Simple Summary Hypoxia is a common feature of lung cancers. Nonetheless, no guidelines
have been established to integrate hypoxia-associated biomarkers in patient management …

Extracellular vesicles derived from lung cancer cells exposed to intermittent hypoxia upregulate programmed death ligand 1 expression in macrophages

Y Liu, M Lu, J Chen, S Li, Y Deng, S Yang, Q Ou, J Li… - Sleep and …, 2022 - Springer
Purpose Intermittent hypoxia (IH), a hallmark of obstructive sleep apnea (OSA),
compromises immune surveillance through the upregulation of programmed cell death-1 …

The association of sleep disorders, obesity and sleep-related hypoxia with cancer

A Brzecka, K Sarul, T Dyła, M Avila-Rodriguez… - Current …, 2020 - ingentaconnect.com
Background: Sleep disorders have emerged as potential cancer risk factors. Objective: This
review discusses the relationships between sleep, obesity, and breathing disorders with …

A review of obstructive sleep apnea and lung cancer: epidemiology, pathogenesis, and therapeutic options

F Yuan, Y Hu, F Xu, X Feng - Frontiers in Immunology, 2024 - frontiersin.org
Despite undeniable advances in modern medicine, lung cancer still has high morbidity and
mortality rates. Lung cancer is preventable and treatable, and it is important to identify new …

Value of surgical and nonsurgical treatment for sleep apnea: a closer look at health care utilization

M Abdelwahab, S Marques, A Huang… - … –Head and Neck …, 2023 - Wiley Online Library
Objective To determine how surgery, continuous positive airway pressure (CPAP), and no
treatment impact health care utilization in patients who have obstructive sleep apnea (OSA) …