Vildagliptin is a representative of Dipeptidyl Peptidase-4 (DPP-4) inhibitors,
antihyperglycemic drugs, approved for use as monotherapy and combination therapy in type …

Abstract Introduction Metabolic Syndrome (MetS) constitutes an important risk factor for
Alzheimer's disease (AD); however, the mechanism linking these two disorders has not …

There is snowballing evidence that type 2 diabetes (T2D) predisposes to
neuropathophysiological alterations including oxidative stress and triggered inflammatory …

Background/Objectives: The effect of dipeptidyl peptidase-4 (DPP-4) inhibitors on plasma
concentrations of adiponectin, a fat-derived hormone with anti-atherogenic and anti …

The objectives of our study were to investigate the possible effect of Simvastatin in
ameliorating high cholesterol diet (HCD)‐induced neurodegeneration and to also …

Objective Chronic high-fat diet consumption causes not only obese-insulin resistance, but
also leads to pathological changes in salivary glands, including increased mitochondrial …

Obesity is a major and rapidly growing global health concern and is known to be associated
with significant morbidity and mortality. The obese state, irrespective of complication, is …

Так, ранее приоритеты при назначении сахароснижающих препаратов отдавались
применению сенситайзерам к инсулину. А в настоящий момент фокус современного …

Incretin effect has a key role in glycemic homeostasis following meals. Glucagon-like
peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) are responsible …

Aims: The mechanisms explaining the trigger of obesity driven neurodegeneration are not
well elucidated. Hypercoagulation followed by hypofibrinolysis mark the pivotal events in the …