Extracellular non-coding RNAs in cardiovascular diseases

Z Jiapaer, C Li, X Yang, L Sun, E Chatterjee, L Zhang… - Pharmaceutics, 2023 - mdpi.com
Cardiovascular diseases (CVDs) remain the world's leading cause of death despite the best
available healthcare and therapy. Emerging as a key mediator of intercellular and inter …

[HTML][HTML] The mechanism of action of non-coding RNAs in placental disorders

S Kannampuzha, M Ravichandran… - Biomedicine & …, 2022 - Elsevier
Placental complication arises due to various risk factors occurring during the pregnancy
period, leading to an increased morbidity rate. Placenta related disorders are one of primary …

The role of cluster C19MC in pre-eclampsia development

I Jaszczuk, I Winkler, D Koczkodaj… - International Journal of …, 2022 - mdpi.com
Pre-eclampsia is a placenta-related complication occurring in 2–10% of all pregnancies.
miRNAs are a group of non-coding RNAs regulating gene expression. There is evidence …

MicroRNAs: key regulators of the trophoblast function in pregnancy disorders

L Liang, Y Chen, C Wu, Z Cao, L Xia, J Meng… - Journal of Assisted …, 2023 - Springer
The placenta is essential for a successful pregnancy and healthy intrauterine development
in mammals. During human pregnancy, the growth and development of the placenta are …

N6-methyladenosine modifications in maternal-fetal crosstalk and gestational diseases

S Wu, K Liu, B Zhou, S Wu - Frontiers in Cell and Developmental …, 2023 - frontiersin.org
As a medium among pregnant women, environment and fetus, placenta owns powerful and
delicate epigenetic processes to regulate gene expression and maintain cellular …

Non-coding RNAs: The link between maternal malnutrition and offspring metabolism

Y Zeng, Y Wu, Q Zhang, X Xiao - Frontiers in Nutrition, 2022 - frontiersin.org
Early life nutrition is associated with the development and metabolism in later life, which is
known as the Developmental Origin of Health and Diseases (DOHaD). Epigenetics have …

Value of Non-Coding RNA Expression in Biofluids to Identify Patients at Low Risk of Pathologies Associated with Pregnancy

AG Cordier, E Zerbib, A Favier, Y Dabi, E Daraï - Diagnostics, 2024 - mdpi.com
Pregnancy-related complications (PRC) impact maternal and fetal morbidity and mortality
and place a huge burden on healthcare systems. Thus, effective diagnostic screening …

Study on the regulation of trophoblast activity by abnormally expressed hsa_circ_0024838/miR-543/HIF1A in patients with gestational diabetes mellitus

Q Liu, J Gui, L Wu - Placenta, 2024 - Elsevier
Introduction This study aimed to screen circRNAs involved in gestational diabetes mellitus
(GDM)-related macrosomia. One differentially expressed circRNA (DEC) …

Placental Conditions With Consequences for the Fetal Brain

AJ du Plessis, JJ Volpe - Volpe's Neurology of the Newborn, 2025 - Elsevier
The normal placenta is far more than a mere conduit for nutrient and waste exchange
between the mother and fetus. Rather, it is a highly specialized organ with multiple complex …

The role of placental non-coding RNAs in adverse pregnancy outcomes

J Ren, H Jin, Y Zhu - International Journal of Molecular Sciences, 2023 - mdpi.com
Non-coding RNAs (ncRNAs) are transcribed from the genome and do not encode proteins.
In recent years, ncRNAs have attracted increasing attention as critical participants in gene …