One essential prokaryotic cell function is the transport of proteins from the cytoplasm into
other compartments of the cell, the environment, and/or other bacteria or eukaryotic cells—a …

Bacteria have evolved a remarkable array of sophisticated nanomachines to export various
virulence factors across the bacterial cell envelope. In recent years, considerable progress …

Signal peptides (SP) are short peptides located in the N-terminal of proteins, carrying
information for protein secretion. They are ubiquitous to all prokaryotes and eukaryotes. SPs …

Proteus mirabilis, a Gram-negative rod-shaped bacterium most noted for its swarming
motility and urease activity, frequently causes catheter-associated urinary tract infections …

Proteus mirabilis is well known in clinical laboratories and microbiology survey courses as
the species that swarms across agar surfaces, overtaking any other species present in the …

The ability of bacterial cells to adhere to and interact with surfaces to eventually form a
biofilm is a crucial trait for the survival of any microorganism in a complex environment. As a …

Bacteria with two cell membranes (diderms) have evolved complex systems for protein
secretion. These systems were extensively studied in some model bacteria, but the …

Controlled human malaria infection (CHMI) entails deliberate infection with malaria
parasites either by mosquito bite or by direct injection of sporozoites or parasitized …

Bacterial colonization of biotic or abiotic surfaces results from two quite distinct physiological
processes, namely bacterial adhesion and biofilm formation. Broadly speaking, a biofilm is …

In this work we report synthetic adhesins (SAs) enabling the rational design of the adhesion
properties of E. coli. SAs have a modular structure comprising a stable β-domain for outer …