A comprehensive survey of the approaches for pathway analysis using multi-omics data integration
Pathway analysis has been widely used to detect pathways and functions associated with
complex disease phenotypes. The proliferation of this approach is due to better …
complex disease phenotypes. The proliferation of this approach is due to better …
A New Understanding of Long Non-Coding RNA in Hepatocellular Carcinoma—From m6A Modification to Blood Biomarkers
With recent advancements in biological research, long non-coding RNAs (lncRNAs) with
lengths exceeding 200 nucleotides have emerged as pivotal regulators of gene expression …
lengths exceeding 200 nucleotides have emerged as pivotal regulators of gene expression …
lncRNAfunc: a knowledgebase of lncRNA function in human cancer
The long non-coding RNAs associating with other molecules can coordinate several
physiological processes and their dysfunction can impact diverse human diseases. To date …
physiological processes and their dysfunction can impact diverse human diseases. To date …
The 2022 Nucleic Acids Research database issue and the online molecular biology database collection
DJ Rigden, XM Fernández - Nucleic acids research, 2022 - academic.oup.com
Abstract The 2022 Nucleic Acids Research Database Issue contains 185 papers, including
87 papers reporting on new databases and 85 updates from resources previously published …
87 papers reporting on new databases and 85 updates from resources previously published …
Long noncoding RNA NEAT1 promotes cardiac fibrosis in heart failure through increased recruitment of EZH2 to the Smad7 promoter region
Z Ge, C Yin, Y Li, D Tian, Y Xiang, Q Li, Y Tang… - Journal of translational …, 2022 - Springer
Cardiac fibrosis, a well-known major pathological process that ultimately leads to heart
failure, has attracted increasing attention and focus in recent years. A large amount of …
failure, has attracted increasing attention and focus in recent years. A large amount of …
Notch signaling pathway: a comprehensive prognostic and gene expression profile analysis in breast cancer
Breast cancer is a complex disease exhibiting a great degree of heterogeneity due to
different molecular subtypes. Notch signaling regulates the differentiation of breast epithelial …
different molecular subtypes. Notch signaling regulates the differentiation of breast epithelial …
Performance evaluation of differential splicing analysis methods and splicing analytics platform construction
K Li, T Luo, Y Zhu, Y Huang, A Wang… - Nucleic Acids …, 2022 - academic.oup.com
A proportion of previously defined benign variants or variants of uncertain significance in
humans, which are challenging to identify, may induce an abnormal splicing process. An …
humans, which are challenging to identify, may induce an abnormal splicing process. An …
System biology analysis to develop diagnostic biomarkers, monitoring pathological indexes, and novel therapeutic approaches for immune targeting based on maggot …
Early diagnosis and prognosis are prerequisites for mitigating mortality in gastric cancer
(GaCa). Identifying some causative or sensitive elements (coding RNA (cRNA)-non-cRNAs …
(GaCa). Identifying some causative or sensitive elements (coding RNA (cRNA)-non-cRNAs …
Advances in non-coding RNA sequencing
Non-coding RNAs (ncRNAs) comprise a set of abundant and functionally diverse RNA
molecules. Since the discovery of the first ncRNA in the 1960s, ncRNAs have been shown to …
molecules. Since the discovery of the first ncRNA in the 1960s, ncRNAs have been shown to …
Transcriptomes of human primary skin fibroblasts of healthy individuals reveal age‐associated mRNAs and long noncoding RNAs
D Tsitsipatis, JL Martindale, K Mazan‐Mamczarz… - Aging …, 2023 - Wiley Online Library
Abstract Changes in the transcriptomes of human tissues with advancing age are poorly
cataloged. Here, we sought to identify the coding and long noncoding RNAs present in …
cataloged. Here, we sought to identify the coding and long noncoding RNAs present in …