Updates on HTLV-1 uveitis

K Kamoi, T Watanabe, K Uchimaru, A Okayama, S Kato… - Viruses, 2022 - mdpi.com
HTLV-1 uveitis (HU) is the third clinical entity to be designated as an HTLV-1-associated
disease. Although HU is considered to be the second-most frequent HTLV-1-associated …

Dry eye disease caused by viral infection: Past, present and future

M Wu, C Sun, Q Shi, Y Luo, Z Wang, J Wang, Y Qin… - Virulence, 2024 - Taylor & Francis
Following viral infection, the innate immune system senses viral products, such as viral
nucleic acids, to activate innate defence pathways, leading to inflammation and apoptosis …

Ripasudil as a Potential Therapeutic Agent in Treating Secondary Glaucoma in HTLV-1-Uveitis: An In Vitro Analysis

M Yang, K Kamoi, Y Zong, J Zhang, Y Zou… - International Journal of …, 2024 - mdpi.com
Human T-cell leukemia virus type 1 (HTLV-1), a virus that affects 5–10 million people
globally, causes several diseases, including adult T-cell leukemia-lymphoma and HTLV-1 …

RGS7-ATF3-Tip60 complex promotes hepatic steatosis and fibrosis by directly inducing TNFα

M Basak, K Das, T Mahata, AS Sengar… - Antioxidants & Redox …, 2023 - liebertpub.com
Aims: The pathophysiological mechanism (s) underlying non-alcoholic fatty liver disease
(NAFLD) have yet to be fully delineated and only a single drug, peroxisome proliferator …

Current challenges facing the clinical treatment for HTLV-1 ocular manifestations

K Kamoi - Expert Review of Ophthalmology, 2023 - Taylor & Francis
Introduction Human T-lymphotropic virus type 1 (HTLV-1) is a lifelong persistent retrovirus
associated with numerous systemic and ocular diseases, presenting significant clinical …

Mechanism of secondary glaucoma development in HTLV-1 uveitis

Y Zong, K Kamoi, N Ando, H Kurozumi-Karube… - Frontiers in …, 2022 - frontiersin.org
Human T-cell lymphotropic virus type 1 (HTLV-1) was the first retrovirus identified as the
causative agent of human diseases, such as adult T-cell leukemia, HTLV-1-associated …

Safety of intraocular anti-VEGF antibody treatment under in vitro HTLV-1 infection

Y Zong, K Kamoi, H Kurozumi-Karube, J Zhang… - Frontiers in …, 2023 - frontiersin.org
Introduction HTLV-1 (human T-cell lymphotropic virus type 1) is a retrovirus that infects
approximately 20 million people worldwide. Many diseases are caused by this virus …

[HTML][HTML] Effect of adalimumab as an anti-inflammatory agent on gene expression of retinal pigment epithelial cells

MH Nowroozzadeh, M Yousefi, M Abuali… - Biomedicine & …, 2024 - Elsevier
Adalimumab (ADA) is an anti-inflammatory antibody that has FDA approval as a systemic
medication for treating noninfectious uveitis. It is also provisionally being investigated as an …

Evaluating tocilizumab safety and immunomodulatory effects under ocular HTLV-1 infection in vitro

J Zhang, K Kamoi, Y Zong, M Yang, Y Zou… - International …, 2024 - Elsevier
There is growing interest in evaluating the safety and therapeutic potential of existing
treatments such as tocilizumab (TCZ), an IL-6 receptor antagonist used to treat inflammatory …

Clinical course of HTLV-1 infection associated intermediate uveitis

C Siverio-Llosa, I Silva-Ocas, T Gálvez-Olórtegui… - Archivos de la Sociedad …, 2022 - Elsevier
Objective To describe the clinical features at presentation, delivered treatment and follow-up
of a case series of human T-cell lymphotropic virus type 1 (HTLV-1) associated intermediate …