The male factor contributes to 50% of infertility. The cause of male infertility is idiopathic and
could be congenital or acquired. Among different factors which are involved in idiopathic …

The male reproductive system is acutely and uniquely sensitive to a variety of toxicities,
including those induced by environmental pollutants throughout the lifespan. Early life …

Published data on the association between the GST genes polymorphisms and male
infertility risk are inconclusive. We investigated GST genes polymorphisms in a large sample …

Background: The aim of this case–control study is to investigate possible associations
between GSTM1 polymorphism and redox potential with sperm parameters. Methods: The …

Inconsistent results of association studies investigated the role of glutathione S–transferase
genes in idiopathic male infertility may be explained by ethnical differences in gene–gene …

Background Male infertility is a complex disorder caused by genetic, developmental,
endocrine, or environmental factors as well as unknown etiology. Polymorphisms in the …

Background Cytochrome P450 (CYP) genes are necessary for the production or metabolism
of fetal sex hormones during pregnancy. The second-to-fourth digit ratio (2D: 4D) is formed …

The study was designed to investigate the associations of polymorphisms Ile462Val and
3801T> C of the cytochrome P450 1A1 (CYP1A1) gene with idiopathic male infertility (IMI) …

Oxidative stress is increased in chronic kidney disease, owing to an imbalance between the
oxidative and antioxidant pathways as well as a state of persistent hyperhomocysteinemia …

Studies of the relationship between male infertility and CYP1A1 polymorphisms are
inconclusive. To drive a more precise estimation, we performed a meta-analysis based on …