The role of macrophages in HIV-1 persistence and pathogenesis

Z Kruize, NA Kootstra - Frontiers in microbiology, 2019 - frontiersin.org
Current antiretroviral therapy (ART) effectively suppresses Human Immunodeficiency Virus
type 1 (HIV-1) in infected individuals. However, even long term ART does not eradicate HIV …

An integrated overview of HIV-1 latency

DS Ruelas, WC Greene - Cell, 2013 - cell.com
Despite significant advances in our understanding of HIV, a cure has not been realized for
the more than 34 million infected with this virus. HIV is incurable because infected …

[图书][B] Fields' virology

BN Fields - 2007 - books.google.com
Established for 20 years as the definitive virology reference, the two-volume classic Fields
Virology is in its thoroughly revised, updated Fifth Edition. More than 100 world-renowned …

Decay characteristics of HIV-1-infected compartments during combination therapy

AS Perelson, P Essunger, Y Cao, M Vesanen, A Hurley… - Nature, 1997 - nature.com
Abstract Analysis of changes in viral load after initiation of treatment with potent antiretroviral
agents has provided substantial insight into the dynamics of human immunodeficiency virus …

How does HIV cause AIDS?

RA Weiss - Science, 1993 - science.org
Many questions have been posed about acquired immunodeficiency syndrome (AIDS)
pathogenesis. Is human immunodeficiency virus (HIV) both necessary and sufficient to …

Mineralocorticoid action: target tissue specificity is enzyme, not receptor, mediated

JW Funder, PT Pearce, R Smith, AI Smith - Science, 1988 - science.org
Mineralocorticoid receptors, both when in tissue extracts and when recombinant-derived,
have equal affinity for the physiological mineralocorticoid aldosterone and for the …

Pathogenesis of human immunodeficiency virus infection

JA Levy - Microbiological reviews, 1993 - Am Soc Microbiol
The lentivirus human immunodeficiency virus (HIV) causes AIDS by interacting with a large
number of different cells in the body and escaping the host immune response against it. HIV …

Biological Invasion by Myrica faya Alters Ecosystem Development in Hawaii

PM Vitousek, LR Walker, LD Whiteaker… - Science, 1987 - science.org
The exotic nitrogen-fixing tree Myrica faya invades young volcanic sites where the growth of
native plants is limited by a lack of nitrogen. Myrica quadruples the amount of nitrogen …

Detection of AIDS virus in macrophages in brain tissue from AIDS patients with encephalopathy

S Koenig, HE Gendelman, JM Orenstein… - Science, 1986 - science.org
One of the common neurological complications in patients with the acquired immune
deficiency syndrome (AIDS) is a subacute encephalopathy with progressive dementia. By …

The challenge of viral reservoirs in HIV-1 infection

JN Blankson, D Persaud… - Annual review of …, 2002 - annualreviews.org
▪ Abstract A viral reservoir is a cell type or anatomical site in association with which a
replication-competent form of the virus accumulates and persists with more stable kinetic …