MHC antigen presentation plays a fundamental role in adaptive and semi-invariant T cell
immunity. Distinct MHC molecules bind antigens that differ in chemical structure, origin and …

Metabolite-based T-cell immunity is emerging as a major player in antimicrobial immunity,
autoimmunity, and cancer. Here, small-molecule metabolites were identified to be captured …

Mucosal-associated invariant T (MAIT) cells are a subset of T lymphocytes that respond to
microbial metabolites. We defined MAIT cell populations in different organs and …

Mucosal-associated invariant T (MAIT) cells use canonical semi-invariant T cell receptors
(TCR) to recognize microbial riboflavin precursors displayed by the antigen-presenting …

Mucosal-associated invariant T (MAIT) cells are antimicrobial T cells abundant in the gut, but
mechanisms for their migration into tissues during inflammation are poorly understood …

Mucosa-associated invariant T (MAIT) cells are evolutionarily conserved, innate-like T
lymphocytes with enormous immunomodulatory potentials. Due to their strategic …

Mucosal-associated invariant T (MAIT) cells are a subset of unconventional T cells that
recognize small molecule metabolites presented by major histocompatibility complex class I …

Mucosal-associated invariant T (MAIT) cells are essential in defending against infection.
Sepsis is a systemic inflammatory response to infection and a leading cause of death. The …

Understanding the immunological control of pathogens requires a detailed evaluation of the
mechanistic contributions of individual cell types within the immune system. While knockout …

Introduction Mucosal-associated invariant T (MAIT) cells are a population of innate-like T
cells, which mediate host immunity to microbial infection by recognizing metabolite antigens …