Therapeutic strategies targeting inflammation and immunity in atherosclerosis: how to proceed?
SE Engelen, AJB Robinson, YX Zurke… - Nature Reviews …, 2022 - nature.com
Atherosclerosis is a chronic inflammatory disease of the arterial wall, characterized by the
formation of plaques containing lipid, connective tissue and immune cells in the intima of …
formation of plaques containing lipid, connective tissue and immune cells in the intima of …
How the immune system shapes atherosclerosis: roles of innate and adaptive immunity
P Roy, M Orecchioni, K Ley - Nature Reviews Immunology, 2022 - nature.com
Atherosclerosis is the root cause of many cardiovascular diseases. Extensive research in
preclinical models and emerging evidence in humans have established the crucial roles of …
preclinical models and emerging evidence in humans have established the crucial roles of …
[PDF][PDF] Low-density lipoproteins cause atherosclerotic cardiovascular disease: pathophysiological, genetic, and therapeutic insights: a consensus statement from the …
OP-EHEA191011_online 2313..2340 Page 1 Low-density lipoproteins cause atherosclerotic
cardiovascular disease: pathophysiological, genetic, and therapeutic insights: a consensus …
cardiovascular disease: pathophysiological, genetic, and therapeutic insights: a consensus …
Diversity, mechanisms, and significance of macrophage plasticity
M Locati, G Curtale, A Mantovani - Annual Review of Pathology …, 2020 - annualreviews.org
Macrophages are a diverse set of cells present in all body compartments. This diversity is
imprinted by their ontogenetic origin (embryonal versus adult bone marrow–derived cells); …
imprinted by their ontogenetic origin (embryonal versus adult bone marrow–derived cells); …
Apolipoproteins in vascular biology and atherosclerotic disease
A Mehta, MD Shapiro - Nature Reviews Cardiology, 2022 - nature.com
Apolipoproteins are important structural components of plasma lipoproteins that influence
vascular biology and atherosclerotic disease pathophysiology by regulating lipoprotein …
vascular biology and atherosclerotic disease pathophysiology by regulating lipoprotein …
2019 ESC/EAS Guidelines for the management of dyslipidaemias: lipid modification to reduce cardiovascular risk The Task Force for the management of …
F Mach, C Baigent, AL Catapano… - European heart …, 2020 - academic.oup.com
version of the Guidelines, which is freely available via the ESC and EAS websites and
hosted on their journals' websites (EHJ and Atherosclerosis Journal). The National Cardiac …
hosted on their journals' websites (EHJ and Atherosclerosis Journal). The National Cardiac …
Single-cell immune landscape of human atherosclerotic plaques
DM Fernandez, AH Rahman, NF Fernandez… - Nature medicine, 2019 - nature.com
Atherosclerosis is driven by multifaceted contributions of the immune system within the
circulation and at vascular focal sites. However, specific characteristics of dysregulated …
circulation and at vascular focal sites. However, specific characteristics of dysregulated …
Treatment of atherosclerosis by macrophage-biomimetic nanoparticles via targeted pharmacotherapy and sequestration of proinflammatory cytokines
C Gao, Q Huang, C Liu, CHT Kwong, L Yue… - Nature …, 2020 - nature.com
Vascular disease remains the leading cause of death and disability, the etiology of which
often involves atherosclerosis. The current treatment of atherosclerosis by pharmacotherapy …
often involves atherosclerosis. The current treatment of atherosclerosis by pharmacotherapy …
Targeting early atherosclerosis: a focus on oxidative stress and inflammation
P Marchio, S Guerra-Ojeda, JM Vila… - Oxidative medicine …, 2019 - Wiley Online Library
Atherosclerosis is a chronic vascular inflammatory disease associated to oxidative stress
and endothelial dysfunction. Oxidation of low‐density lipoprotein (LDL) cholesterol is one of …
and endothelial dysfunction. Oxidation of low‐density lipoprotein (LDL) cholesterol is one of …
[HTML][HTML] Inflammation and cardiovascular disease: From mechanisms to therapeutics
Inflammation constitutes a complex, highly conserved cascade of molecular and cellular
events. Inflammation has been labeled as “the fire within,” is highly regulated, and is critical …
events. Inflammation has been labeled as “the fire within,” is highly regulated, and is critical …