Mechanism of epithelial‐mesenchymal transition in cancer and its regulation by natural compounds
HL Ang, CD Mohan, MK Shanmugam… - Medicinal research …, 2023 - Wiley Online Library
Epithelial‐mesenchymal transition (EMT) is a complex process with a primordial role in
cellular transformation whereby an epithelial cell transforms and acquires a mesenchymal …
cellular transformation whereby an epithelial cell transforms and acquires a mesenchymal …
Shikonin, a naphthalene ingredient: Therapeutic actions, pharmacokinetics, toxicology, clinical trials and pharmaceutical researches
Q Sun, T Gong, M Liu, S Ren, H Yang, S Zeng, H Zhao… - Phytomedicine, 2022 - Elsevier
Background Shikonin is one of the major phytochemical components of Lithospermum
erythrorhizon (Purple Cromwell), which is a type of medicinal herb broadly utilized in …
erythrorhizon (Purple Cromwell), which is a type of medicinal herb broadly utilized in …
Berberine is a suppressor of Hedgehog signaling cascade in colorectal cancer
Q Sun, Q Tao, T Ming, S Tang, H Zhao, M Liu, H Yang… - Phytomedicine, 2023 - Elsevier
Background Colorectal cancer (CRC) is a malignant affliction that burdens people globally.
Overactivated Hedgehog signal is highly implicated in CRC pathogenesis. Phytochemical …
Overactivated Hedgehog signal is highly implicated in CRC pathogenesis. Phytochemical …
[HTML][HTML] Ferroptosis-induced anticancer effect of resveratrol with a biomimetic nano-delivery system in colorectal cancer treatment
Z Zhang, Y Ji, N Hu, Q Yu, X Zhang, J Li, F Wu… - Asian Journal of …, 2022 - Elsevier
Ferroptosis is a novel form of programmed cell death impelled by iron-dependent lipid
peroxidation, which may be a potential strategy for cancer therapy. Here we demonstrated …
peroxidation, which may be a potential strategy for cancer therapy. Here we demonstrated …
Efficacy evaluation, active ingredients, and multitarget exploration of herbal medicine
J Ren, L Yang, S Qiu, AH Zhang, XJ Wang - Trends in Endocrinology & …, 2023 - cell.com
Evidence shows that herbal medicine (HM) could be beneficial for the treatment of various
diseases. However, complexities present in HM due to the unclear bioactive compounds …
diseases. However, complexities present in HM due to the unclear bioactive compounds …
Multi-omics approaches for in-depth understanding of therapeutic mechanism for Traditional Chinese Medicine
Traditional Chinese Medicine (TCM) is extensively utilized in clinical practice due to its
therapeutic and preventative treatments for various diseases. With the development of high …
therapeutic and preventative treatments for various diseases. With the development of high …
Berberine Suppresses Stemness and Tumorigenicity of Colorectal Cancer Stem-Like Cells by Inhibiting m6A Methylation
Z Zhao, J Zeng, Q Guo, K Pu, Y Yang, N Chen… - Frontiers in …, 2021 - frontiersin.org
Background Cancer stem cells (CSCs) are able to survive after cancer therapies, resulting in
tumor progression and recurrence, as is seen in colorectal cancer. Therapies targeting …
tumor progression and recurrence, as is seen in colorectal cancer. Therapies targeting …
Luteolin, a flavone ingredient: Anticancer mechanisms, combined medication strategy, pharmacokinetics, clinical trials, and pharmaceutical researches
M Shi, Z Chen, H Gong, Z Peng, Q Sun… - Phytotherapy …, 2024 - Wiley Online Library
Current pharmaceutical research is energetically excavating the pharmacotherapeutic role
of herb‐derived ingredients in multiple malignancies' targeting. Luteolin is one of the major …
of herb‐derived ingredients in multiple malignancies' targeting. Luteolin is one of the major …
Antitumor effects of Chinese herbal medicine compounds and their nano-formulations on regulating the immune system microenvironment
K Sun, L Wu, S Wang, W Deng - Frontiers in Oncology, 2022 - frontiersin.org
Traditional Chinese medicine (TCM), including herbal medicine, acupuncture and
meditation, has a wide range of applications in China. In recent years, herbal compounding …
meditation, has a wide range of applications in China. In recent years, herbal compounding …
Licochalcone B induces DNA damage, cell cycle arrest, apoptosis, and enhances TRAIL sensitivity in hepatocellular carcinoma cells
Y Zhang, P Feng, H Wang, H Zhang, T Liang… - Chemico-Biological …, 2022 - Elsevier
Hepatocellular carcinoma (HCC) is a highly fatal disease recognized as a growing global
health crisis. Traditional Chinese herbal medicines have been used to treat patients with …
health crisis. Traditional Chinese herbal medicines have been used to treat patients with …