Efficacy and safety of antidepressants added to antipsychotics for schizophrenia: a systematic review and meta-analysis

B Helfer, MT Samara, M Huhn, E Klupp… - American Journal of …, 2016 - Am Psychiatric Assoc
Objective: The authors examined the safety and efficacy of antidepressants added to
antipsychotic drugs in the treatment of schizophrenia. Method: Multiple databases and …

Secondary negative symptoms—a review of mechanisms, assessment and treatment

M Kirschner, A Aleman, S Kaiser - Schizophrenia research, 2017 - Elsevier
Negative symptoms in schizophrenia may be classified as primary or secondary. Primary
negative symptoms are thought to be intrinsic to schizophrenia, while secondary negative …

Schizophrenia,“Just the Facts” 5. Treatment and prevention Past, present, and future

R Tandon, HA Nasrallah, MS Keshavan - Schizophrenia research, 2010 - Elsevier
The introduction of second-generation antipsychotics and cognitive therapies for
schizophrenia over the past two decades generated considerable optimism about …

Evidence-based guidelines for the pharmacological treatment of schizophrenia: recommendations from the British Association for Psychopharmacology

TRE Barnes… - Journal of …, 2011 - journals.sagepub.com
These guidelines from the British Association for Psychopharmacology address the scope
and targets of pharmacological treatment for schizophrenia. A consensus meeting, involving …

Suicide risk in schizophrenia: learning from the past to change the future

M Pompili, XF Amador, P Girardi… - Annals of general …, 2007 - Springer
Suicide is a major cause of death among patients with schizophrenia. Research indicates
that at least 5–13% of schizophrenic patients die by suicide, and it is likely that the higher …

Multi-target strategies for the improved treatment of depressive states: conceptual foundations and neuronal substrates, drug discovery and therapeutic application

MJ Millan - Pharmacology & therapeutics, 2006 - Elsevier
Major depression is a debilitating and recurrent disorder with a substantial lifetime risk and a
high social cost. Depressed patients generally display co-morbid symptoms, and depression …

Schizophrenia,“just the facts”: what we know in 2008: part 1: overview

R Tandon, MS Keshavan, HA Nasrallah - Schizophrenia research, 2008 - Elsevier
For every disorder, there is a set of established findings and accepted constructs upon which
further understanding is built. The concept of schizophrenia as a disease entity has been …

Evidence-based guidelines for the pharmacological treatment of schizophrenia: updated recommendations from the British Association for Psychopharmacology

TRE Barnes, R Drake, C Paton… - Journal of …, 2020 - journals.sagepub.com
These updated guidelines from the British Association for Psychopharmacology replace the
original version published in 2011. They address the scope and targets of pharmacological …

The schizophrenia syndrome, circa 2024: What we know and how that informs its nature

R Tandon, H Nasrallah, S Akbarian… - Schizophrenia …, 2024 - Elsevier
With new data about different aspects of schizophrenia being continually generated, it
becomes necessary to periodically revisit exactly what we know. Along with a need to review …

Comorbid major depressive disorder in schizophrenia: a systematic review and meta-analysis

D Etchecopar-Etchart, T Korchia… - Schizophrenia …, 2021 - academic.oup.com
Comorbid major depressive disorder (MDD) in schizophrenia (SZ; SZ-MDD) has been
identified as a major prognostic factor. However, the prevalence and associated factors of …