Cancer therapeutic siRNA delivery and imaging by nitrogen-and neodymium-doped graphene quantum dots

AR Valimukhametova, BH Lee… - ACS Biomaterials …, 2023 - ACS Publications
While small interfering RNA (siRNA) technology has become a powerful tool that can enable
cancer-specific gene therapy, its translation to the clinic is still hampered by the inability of …

Elimination of Cancer Cells in Co-Culture: Role of Different Nanocarriers in Regulation of CD47 and Calreticulin-Induced Phagocytosis

EM Hassan, S McWhirter, GC Walker… - … Applied Materials & …, 2023 - ACS Publications
Under healthy conditions, pro-and anti-phagocytic signals are balanced. Cluster of
Differentiation 47 (CD47) is believed to act as an anti-phagocytic marker that is highly …

Exploring ncRNA-mediated pathways in sepsis-induced pyroptosis

AA Bhat, Y Riadi, M Afzal, P Bansal, H Kaur… - … -Research and Practice, 2024 - Elsevier
Sepsis, a potentially fatal illness caused by an improper host response to infection, remains
a serious problem in the world of healthcare. In recent years, the role of ncRNA has …

[HTML][HTML] Pharmaceutical applications of framework nucleic acids

L Chen, J Zhang, Z Lin, Z Zhang, M Mao, J Wu… - … Pharmaceutica Sinica B, 2022 - Elsevier
DNA is a biological polymer that encodes and stores genetic information in all living
organism. Particularly, the precise nucleobase pairing inside DNA is exploited for the self …

Tumor microenvironment-activated cancer cell membrane-liposome hybrid nanoparticle-mediated synergistic metabolic therapy and chemotherapy for non-small cell …

W Zhang, C Gong, Z Chen, M Li, Y Li, J Gao - Journal of …, 2021 - Springer
Background Biomimetic nanotechnology-based RNA interference (RNAi) has been
successful in improving theranostic efficacy in malignant tumors. Its integration with hybrid …

Nanotechnology-based siRNA delivery systems to overcome tumor immune evasion in cancer immunotherapy

K Deng, D Yang, Y Zhou - Pharmaceutics, 2022 - mdpi.com
Immune evasion is a common reason causing the failure of anticancer immune therapy.
Small interfering RNA (siRNA), which can activate the innate and adaptive immune system …

Polymeric Micelles Loaded In Situ Gel with Prednisolone Acetate for Ocular Inflammation: Development and Evaluation

N Kaushal, M Kumar, A Tiwari, V Tiwari, K Sharma… - …, 2023 - Taylor & Francis
Aim: Our study developed a prednisolone acetate polymeric micelles (PM) system for ocular
inflammation related to allergic uveitis. Methods: For PM development, a thin-film hydration …

Nanoparticles as drug delivery systems in the treatment of oral squamous cell carcinoma: current status and recent progression

S Cui, H Liu, G Cui - Frontiers in Pharmacology, 2023 - frontiersin.org
Oral squamous cell carcinoma (OSCC) is a common human malignancy with an estimated
incidence of around 377,713 new cases worldwide in 2020. Despite the advance in clinical …

Engineering Bifunctional Calcium Alendronate Gene‐Delivery Nanoneedle for Synergistic Chemo/Immuno‐Therapy Against HER2 Positive Ovarian Cancer

G Chen, L Zeng, B Bi, X Huang, M Qiu… - Advanced …, 2023 - Wiley Online Library
Ovarian cancer is the most lethal gynecological malignancy. Most patients are diagnosed at
an advanced stage with widespread peritoneal dissemination and ascites. Bispecific T‐cell …

Inorganic nanocarriers for siRNA delivery for cancer treatments

G Kandasamy, D Maity - Biomedical Materials, 2024 - iopscience.iop.org
RNA interference is one of the emerging methodologies utilized in the treatment of a wide
variety of diseases including cancer. This method specifically uses therapeutic RNAs …