RNA interference is one of the emerging methodologies utilized in the treatment of a wide
variety of diseases including cancer. This method specifically uses therapeutic RNAs …

Cancer remains an issue on a global scale. It is estimated that nearly 10 million people
succumbed to cancer worldwide in 2020. New treatment options are urgently needed. A …

Circular RNAs (circRNAs) have been recognized as key components in the intricate
regulatory network of the KRAS pathway across various cancers. The KRAS pathway, a …

Endogenous microRNAs (miRNA) in tumors are currently under exhaustive investigation as
potential therapeutic agents for cancer treatment. Nevertheless, RNase degradation …

Nucleic acid drugs are attracting significant attention as prospective therapeutics. However,
their efficacy is hindered by challenges in penetrating cell membranes and reaching target …

Ultrasound nanodroplets (NDs) have been reported as a promising nanocarrier for siRNA
delivery depending on its unique strengths of sonoporation. Presently, common means for …

Gliomas are central nervous system tumors originating from glial cells, whose incidence and
mortality rise in coming years. The current treatment of gliomas is surgery combined with …

Lung cancer remains the leading cause of cancer‐related deaths worldwide, and
conventional treatments for the disease often fall short. Smart nanoparticles (NPs) are …

Purpose The abnormal activation of NLRP3 inflammasome is related to the occurrence and
development of ulcerative colitis (UC). However, the ideal drug and delivery system remain …

CRISPR, as an emerging gene editing technology, has been widely used in multiple fields
due to its convenient operation, less cost, high efficiency and precision. This robust and …