Glioblastoma (GBM) is the most common brain cancer characterized by aggressive and
infiltrated tumors. For this, hybrid biopolymer-lipid nanoparticles coated with biopolymers …

With the understanding of microRNA (miRNA or miR) functions in tumor initiation,
progression, and metastasis, efforts are underway to develop new miRNA-based therapies …

Cell surface thiols can be targeted by thiol-reactive groups of various materials such as
peptides, nanoparticles, and polymers. Here, we used the maleimide group, which can …

Alcoholic liver disease (ALD) results from continuous and heavy alcohol consumption. The
current treatment strategy for ALD is based on alcohol withdrawal coupled with antioxidant …

In order to identify new targets and treatment modalities for breast cancer, we searched the
literature for circular RNAs (circRNAs) with efficacy in preclinical breast cancer-related in …

The recent focus of cancer therapeutics research revolves around modulating the
immunosuppressive tumor microenvironment (TME) to enhance efficacy. The tumor stroma …

Circular RNAs (circRNAs) are a class of highly stable and closed-loop noncoding RNA that
are involved in the occurrence and development of hepatocellular carcinoma (HCC) …

Different therapeutic practices for treating cancers have significantly evolved to compensate
and/or overcome the failures in conventional methodologies. The demonstrated potentiality …

Iron oxide nanoparticles are one of the nanocarriers that are suitable for novel drug delivery
systems due to low toxicity, biocompatibility, loading capacity, and controlled drug delivery to …

The aim of this study was to explore the efficacy and safety of TGFβ1 siRNA lipid
nanoparticles (LNPs) modified with different PEG derivatives (PEG5000 cholesterol …