Precision medicine for genetic epilepsy on the horizon: Recent advances, present challenges, and suggestions for continued progress
JK Knowles, I Helbig, CS Metcalf, LS Lubbers… - …, 2022 - Wiley Online Library
The genetic basis of many epilepsies is increasingly understood, giving rise to the possibility
of precision treatments tailored to specific genetic etiologies. Despite this, current medical …
of precision treatments tailored to specific genetic etiologies. Despite this, current medical …
Zebrafish larvae as a behavioral model in neuropharmacology
Zebrafish larvae show a clear and distinct pattern of swimming in response to light and dark
conditions, following the development of a swim bladder at 4 days post fertilization. This …
conditions, following the development of a swim bladder at 4 days post fertilization. This …
Making sense of rodent models of anhedonia
S Scheggi, MG De Montis… - International Journal of …, 2018 - academic.oup.com
A markedly reduced interest or pleasure in activities previously considered pleasurable is a
main symptom in mood disorder and psychosis and is often present in other psychiatric …
main symptom in mood disorder and psychosis and is often present in other psychiatric …
Cardiovascular toxicity assessment of polyethylene nanoplastics on developing zebrafish embryos
M Sun, R Ding, Y Ma, Q Sun, X Ren, Z Sun, J Duan - Chemosphere, 2021 - Elsevier
Environmental exposure to nanoplastics is inevitable as the application of nanoplastics in
our daily life is more and more extensively. So, the adverse effects of nanoplastics on human …
our daily life is more and more extensively. So, the adverse effects of nanoplastics on human …
Animal models of pain: diversity and benefits
C Abboud, A Duveau, R Bouali-Benazzouz… - Journal of neuroscience …, 2021 - Elsevier
Chronic pain is a maladaptive neurological disease that remains a major health problem. A
deepening of our knowledge on mechanisms that cause pain is a prerequisite to developing …
deepening of our knowledge on mechanisms that cause pain is a prerequisite to developing …
Zebrafish as an animal model for drug discovery in Parkinson's disease and other movement disorders: a systematic review
RL Vaz, TF Outeiro, JJ Ferreira - Frontiers in neurology, 2018 - frontiersin.org
Movement disorders can be primarily divided into hypokinetic and hyperkinetic. Most of the
hypokinetic syndromes are associated with the neurodegenerative disorder Parkinson's …
hypokinetic syndromes are associated with the neurodegenerative disorder Parkinson's …
[HTML][HTML] The Free-movement pattern Y-maze: A cross-species measure of working memory and executive function
M Cleal, BD Fontana, DC Ranson, SD McBride… - Behavior research …, 2021 - Springer
Numerous neurodegenerative and psychiatric disorders are associated with deficits in
executive functions such as working memory and cognitive flexibility. Progress in developing …
executive functions such as working memory and cognitive flexibility. Progress in developing …
Graphene quantum dots against human IAPP aggregation and toxicity in vivo
The development of biocompatible nanomaterials has become a new frontier in the
detection, treatment and prevention of human amyloid diseases. Here we demonstrated the …
detection, treatment and prevention of human amyloid diseases. Here we demonstrated the …
Triadimenol promotes the production of reactive oxygen species and apoptosis with cardiotoxicity and developmental abnormalities in zebrafish
Various types of fungicides, especially triazole fungicides, are used to prevent fungal
diseases on farmlands. However, the developmental toxicity of one of the triazole fungicides …
diseases on farmlands. However, the developmental toxicity of one of the triazole fungicides …
Zebrafish (Danio rerio) as an excellent vertebrate model for the development, reproductive, cardiovascular, and neural and ocular development toxicity study of …
C Shen, Z Zuo - Environmental Science and Pollution Research, 2020 - Springer
In the past decades, the type of chemicals has gradually increased all over the world, and
many of these chemicals may have a potentially toxic effect on human health. The zebrafish …
many of these chemicals may have a potentially toxic effect on human health. The zebrafish …