In many studies, the extensive and significant anticancer activity of chelerythrine (CHE) was
identified, which is the primary natural active compound in four traditional botanical drugs …

Sepsis is a systemic inflammatory response syndrome caused by an infection. Toll-like
receptor 4 (TLR4) is activated by endogenous molecules released by injured or necrotic …

Silver nanoparticles have been used for numerous therapeutic purposes because of their
increased biodegradability and bioavailability, yet their toxicity remains questionable as they …

Tyrosine-protein kinase (Syk) plays a potential role in neuroinflammation and adaptive
immune responses in several neurodegenerative conditions. Seeing the significant role of …

The lipopolysaccharide, a microbial toxin, is one of the major causative agents of sepsis. P-
gp expression and its functions are altered during inflammation. LPS has been known to …

Sepsis-Associated Encephalopathy (SAE) is common in sepsis patients, with high mortality
rates. It is believed that neuroinflammation is an important mechanism involved in SAE. High …

Background: The liver and kidney inflammation due to bacterial infection is one of the most
common pathological problems leading to tissue damage or disease. In many liver and …

Sepsis, a systemic inflammatory response disease, is the most severe complication of
infection and a deadly disease. High mobility group proteins (HMGs) are non-histone …

Abstract Background Ginsenoside Rg3 is one of the main active ingredients in ginseng.
Here, we aimed to confirm its protective effect on the heart function in transverse aortic …

Acute kidney injury (AKI) is a common critical illness that involves multiple systems and
multiple organs with a rapid decline in kidney function over short period. It has a high …