Introduction: Congenital hypopituitarism (CH) is characterized by a deficiency of one or more
pituitary hormones. The pituitary gland is a central regulator of growth, metabolism, and …

The current review is informed about the effectiveness of plant-derived functional
components that aids in the regulation and health of endocrine glands. The endocrine …

Hypopituitarism, or the failure to secrete hormones produced by the anterior pituitary
(adenohypophysis) and/or to release hormones from the posterior pituitary …

Diphthamide is a modified histidine residue unique for eukaryotic translation elongation
factor 2 (eEF2), a key ribosomal protein. Loss of this evolutionarily conserved modification …

Background ISL LIM homeobox 2, also known as insulin gene enhancer protein ISL-2
(ISL2), is a transcription factor gene that participates in a wide range of developmental …

Context Congenital combined pituitary hormone deficiency (cCPHD) is the loss of≥ 2
pituitary hormones caused by congenital factors. Objective We aimed to estimate the …

Ectopic tissue is an anatomic abnormality in which tissue develops in an area outside its
normal location. It is primarily caused by abnormalities during the process of embryologic …

Despite its small size, the pituitary gland plays a central role in the maintenance of normal
homeostasis of most physiological systems through its regulation of the function of other …

In this review article, topics of the embryonic origin of the adenohypophysis and
hypothalamus and the development of the hypothalamo–hypophyseal system for the …

The age-related alterations in pituitary function, including changes in prolactin (PRL)
production contributes to the systemic susceptibility to age-related diseases. Our previous …