A wide range of cytotoxic and mutagenic DNA bases are removed by different DNA
glycosylases, which initiate the base excision repair pathway. DNA glycosylases cleave the …

Drug-metabolizing enzymes are called mixed-function oxidase or monooxygenase and
containing many enzymes including cytochrome P450, cytochrome b5, and NADPH …

Declining cigarette use and spreading bans on smoking in public places in the United States
are encouraging the US cigarette industry to turn to another tobacco category, smokeless …

Cigarette smoking is a major cause of mortality and morbidity worldwide. Cyclooxygenase
(COX) and its derived prostanoids, mainly including prostaglandin E2 (PGE2), thromboxane …

New tobacco products, designed to attract consumers who are concerned about the health
effects of tobacco, have been appearing on the market. Objective evaluation of these …

Cancer remains a major cause of cancer-related death worldwide. Over 70% of epithelial
malignancies are sporadic and are related to lifestyle. Epidemiological studies suggest an …

Tobacco-specific nitrosamines are believed to play a significant role as causes of cancer in
people who use tobacco products. Whereas the uptake of one tobacco-specific nitrosamine …

Smokeless tobacco products are a known cause of oral cancer in India. Carcinogenic
tobacco‐specific nitrosamines in these products are believed to be at least partially …

The role of thromboxane A 2 (TxA 2) in smoking-associated lung cancer is poorly
understood. This study was conducted to study the role of TxA 2 in smoking carcinogen 4 …

We know that cigarette smoking is a leading preventable cause of carcinogenesis in lung
cancer. Cigarette smoke is a mixture of more than 5000 chemical compounds, among which …